17-AAD |
17-N-allylamino-17-demethoxygeldanamycin |
AIs |
Aromatase inhibitors |
AIB1 |
Amplified in breast cancer 1 |
ATM |
Ataxia Telangiectasia Mutated |
BC |
Breast cancer |
CDK |
Cyclin dependent kinases |
CI |
Combination index |
CREB5 |
CAMP Responsive Element Binding Protein 5 |
CREB3L4 |
CAMP Responsive Element Binding Protein 3 Like 4 |
DMSO |
Dimethyl Sulfoxide |
EFGR |
Epidermal growth factor receptor |
ErbB2 |
Erb-B2 Receptor Tyrosine Kinase 2 |
ER |
Estrogen receptor |
ESR1 |
Estrogen receptor 1 |
FAK1 |
Focal adhesion kinase 1 |
FITC |
Fluorescein isothiocyanate |
FOXM1 |
Forkhead box protein M1 |
GAPDH |
Glyceraldehyde 3-phosphate dehydrogenase |
HAA2020
|
compound 1 (4-(2-(4-Oxo-2-thioxo-1,4-dihydroquinazolin-3(2H)-yl)ethyl) benzene sulfonamide) |
Her2 |
Human epidermal growth factor receptor 2 |
Hsp90 |
Heat shock protein 90 |
Hsp90i |
Heat shock protein 90 inhibitors |
HR |
Hormone receptor |
IGFBP2 |
Insulin-like growth factor (IGF) binding protein 2 |
MAPK |
Mitogen activated protein kinase |
MRAS |
Muscle RAS oncogene |
PA |
Pathway analysis |
PCNA |
Proliferating cell nuclear antigen |
PI |
Propidium iodide |
PI3K/AKT |
Phosphoinositide-3-kinases/Protein kinase B |
PIK3C2G |
Phosphatidylinositol-4-Phosphate 3 Kinase Catalytic Subunit Type 2 Gamma |
PKC |
Protein kinase C |
PLC gamma 1 |
Phospholipase C, gamma 1 |
RhoA |
Ras homolog family member A |
RoCK-1 |
Rho Associated Coiled-Coil Containing Protein Kinase 1 |
PR |
Progestrone receptor |
RT-PCR |
Reverse transcription polymerase chain reaction |
SERDs |
Selective estrogen receptor degraders |
SERMs |
Selective estrogen receptor modulators |
SI |
Selectivity index |
SRC |
Proto-oncogene tyrosine-protein kinase |
TKI |
Tyrosine kinase inhibitors |
TRAM-1 |
Translocation Associated Membrane Protein 1 |
VEGF |
Vascular endothelial growth factor |
VEGFR |
Vascular endothelial growth factor receptor |
VEGFR-2 |
Vascular endothelial growth factor receptor-2 |