Table 2.

Top three networks found in the 12 luminal-A Saudi samples.

No	Network Name	Processes	Size	Target	Pathways	p-Value	zScore	gScore
1	VEGFR-2, cRaf-1, FAK1, c-Src, VEGFR-3	Transmembrane receptor protein tyrosine kinase signalling pathway (77.6%), enzyme linked receptor protein signalling pathway (81.6%), locomotion (85.7%), cell morphogenesis (73.5%), cell projection morphogenesis (67.3%).	52	16	56	4.65 × 10−36	70.29	140.29
2	TrkA, LAT, Syk, c-Src, Fer	Peptidyl-tyrosine phosphorylation (58.1%), peptidyl-tyrosine modification (58.1%), transmembrane receptor protein tyrosine kinase signalling pathway (65.1%), positive regulation of ERK1 and ERK2 cascade (55.8%), regulation of ERk1 and ERK2 cascade (58.1%).	53	29	3	1.25 × 10−74	128.86	132.61
3	Ephrin-A receptor 3, YES, Ephrin-A receptor 2, Fer, p130	Transmembrane receptor protein tyrosine kinase signalling pathway (50.0%), regulation of phosphorylation (68.8%), chemotaxis (47.9%), taxis (47.9%), regulation of protein phosphorylation (64.6%).	50	20	5	2.28 × 10−47	88.80	95.05