Table 12.

Types of therapeutic agents used in drug-eluting balloons [14].

Class of Therapeutic Agent	Examples	Mechanism of Action
Antiplatelet	Aspirin, clopidogrel	Reduces blood clotting
Anti-inflammatory	Glucocorticoids, betamethasone, dexamethasone prednisolone	Inhibits monocyte and macrophage function and influences smooth muscle cell proliferation
Antihyperlipidemic	Statins (simvastatin, pravastatin), probucol	Decreases blood cholesterol level
Antiproliferative	Taxanes (paclitaxel docetaxel) limus (sirolimus, everolimus, tacrolimus)	Inhibits the G1 or G2 phase and the proliferation of cells
Cytotoxic antibiotics	Actinomycin-D	Inhibits the G1 phase and the proliferation of cells
Antithrombogenic agents	Heparin, urokinase	Prevents the formation of thrombin