Table 2. Concentrations of Melatonin, Serotonin, and l-Tryptophan in Wine Samples Quantified with HPLC-MS/MS.

origin of wines	geographic Romanian regions	production year	grape variety	melatonin (ng mL–1)	serotonin (ng mL–1)	l-tryptophan (ng mL–1)
markets	Muntenia	2018	White, Sparkling	19.6 ± 0.78	66.6 ± 0.36	700.6 ± 8.69
		2017	White, Riesling	11.8 ± 0.15	24.5 ± 0.21	1450.0 ± 15.24
		2018	White, Riesling	17.0 ± 0.1	33.6 ± 0.52	1768.2 ± 12.36
	Oltenia	2018	Rose, Cabernet Sauvignon	8.4 ± 0.29	5.8 ± 0.32	976.8 ± 5.89
	Moldavia	2018	Red, Cabernet Sauvignon	17.7 ± 0.15	23.3 ± 0.45	550.3 ± 4.25
			Red, Merlot & Pinot Noir	23.0 ± 0.84	12.8 ± 0.08	890.4 ± 7.48
	Oltenia	2014	Red, Merlot	18.0 ± 0.21	5.0 ± 0.02	1262.0 ± 10.25
	Dobruja	2014	Red, Cabernet Sauvignon & Merlot	11.6 ± 0.67	83.4 ± 0.82	1773.5 ± 15.23
small vineyards	Muntenia	2018	White, Noah		12.3 ± 0.08	3.5 ± 0.05
			White, Noah	35.4 ± 0.43	13.2 ± 0.04	1385.2 ± 1.14
	Moldavia	2014	White, Riesling & Feteasca	1.0 ± 0.07	16.8 ± 0.06	49.4 ± 0.07
		2018	White, Cabernet Sauvignon	12.5 ± 0.69	13.2 ± 0.03	1125.4 ± 16.36
	Muntenia	2016	Rose, Lidia	30.8 ± 0.64	21.2 ± 0.05	3038.2 ± 20.12
		2018	Rose, Lidia	32.6 ± 0.57	89.0 ± 1.42	2382.6 ± 19.27
			Rose, Lidiaa	82.6 ± 2.12	265.6 ± 5.25	17 001.0 ± 124.36
			Rose, Riesling & Chasselas	2.0 ± 0.07	72.8 ± 0.11	21.8 ± 0.08
	Moldavia	2018	Rose, Cabernet Sauvignon	5.8 ± 0.07	11.0 ± 0.27	275.0 ± 1.36
			Rose, Cabernet Sauvignon	1.4 ± 0.09	36.4 ± 0.72	5.5 ± 0.04
	Muntenia	2009	Red, Merlot	2.0 ± 0.06	43.2 ± 0.73	5.5 ± 0.03
		2012	Red, Babeasca neagra	3.8 ± 0.08	16.8 ± 0.09	330.4 ± 1.02
		2018	Red, Seibel 1	10.0 ± 0.25	53.6 ± 0.85	805.2 ± 5.78
			Red, Isabelle & Babeasca neagra	11.6 ± 0.33	22.2 ± 0.09	2467.6 ± 18.24
			Red, Seibel 1	1.0 ± 0.02	10.4 ± 0.07	100.5 ± 0.87
	Moldavia	2018	Red, Othello	66.6 ± 1.13	68.8 ± 1.35	6137.0 ± 5.47
			Red Cabernet Sauvignon	4.2 ± 0.07	25.5 ± 1.14	76.0 ± 0.057

^aBold values present the wine with the highest concentration analytes of interest.