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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Stroke. 2020 Oct 26;51(11):3417–3424. doi: 10.1161/STROKEAHA.120.030425

Table 1.

Adjusted Association of Hemostasis Biomarkers with Stroke Risk, REGARDS cohort (hazard ratios and 95% confidence intervals)*

All Black people White people
Factor VIII30
Per SD Higher (44%) 1.26 (1.08, 1.46) 1.26 (1.02, 1.55) 1.26 (1.02, 1.56)
Factor IX27
Per SD higher (22%) 1.03 (0.89, 1.19) 1.00 (0.80, 1.25) 1.05 (0.88, 1.26)
Factor XI27
Per SD higher (25%) 1.08 (0.94, 1.24) 1.01 (0.83, 1.24) 1.12 (0.93, 1.35)
Protein C30
Per SD lower (22%) 1.04 (0.88, 1.23) 0.99 (0.77, 1.26) 1.09 (0.87, 1.35)
D-dimer28
Per doubling 1.15 (1.01, 1.31) 1.12 (0.92, 1.34) 1.19 (0.99, 1.42)

Adjusted for: Age, sex, race, age*race interaction, systolic blood pressure, taking blood pressure medications, diabetes, current smoking, atrial fibrillation, left ventricular hypertrophy, and baseline cardiovascular disease (coronary heart disease or peripheral vascular disease)

*:

p-values for race*biomarker interaction were all >0.10 (non-significant)