Table 3.

ORs (95% CI) for chronic inflammation among women with a history of gestational diabetes, according to lifetime duration of lactation*

	0 month	1–12 months	12–24 months	>24 months	P linear trend	Per 6-month increase	Per 1-year increase
Model 1	1	1.13 (0.66 to 1.96)	0.83 (0.48 to 1.46)	0.59 (0.34 to 1.02)	0.002	0.93 (0.87 to 0.99)	0.87 (0.77 to 0.98)
Model 2	1	1.19 (0.68 to 2.09)	0.82 (0.46 to 1.45)	0.49 (0.27 to 0.89)	0.0003	0.89 (0.82 to 0.96)	0.79 (0.68 to 0.92)
Model 3	1	1.33 (0.75 to 2.37)	0.94 (0.52 to 1.71)	0.55 (0.30 to 1.03)	0.001	0.90 (0.83 to 0.97)	0.81 (0.69 to 0.94)

*Chronic inflammation is assessed using CRP 3 mg/L cut-off (n=224 of 675 above 3 mg/L). Model 1 is adjusted for age at follow-up blood draw. Model 2 is additionally adjusted for ethnicity (white/non-white), family history of diabetes (yes/no), parity, age at first birth (<25, 25–29, 30–34, and ≥35 years) and menopausal status at follow-up blood draw (yes/no). Model 3 is adjusted for model 2 in addition to ever smoking (yes/no), diet quality (high/low), physical activity (high/low), and prepregnancy BMI (≤25, 25–30, and >30 kg/m²).

BMI, body mass index; CRP, C reactive protein.