Table 5.

C-statistics of leukocyte subtypes and C-ACS for predicting cardiovascular mortality

Models	C-statistics (95% CI)	△C-statistics (95% CI)	P value
C-ACS	0.643 (0.600–0.685)	–	–
C-ACS + leukocytes	0.676 (0.626–0.726)	0.033 (0.012–0.055)	0.003
C-ACS + neutrophils	0.695 (0.646–0.744)	0.052 (0.026–0.078)	< 0.001
C-ACS + lymphocytes	0.688 (0.640–0.736)	0.046 (− 0.005 to 0.085)	0.045
C-ACS + monocytes	0.663 (0.615–0.711)	0.020 (0.002–0.039)	0.029
C-ACS + eosinophils	0.686 (0.640–0.733)	0.044(0.021–0.070)	< 0.001
C-ACS + basophils	0.670 (0.623–0.718)	0.028(0.004–0.053)	< 0.026
C-ACS + NMLR	0.722 (0.675–0.768)	0.079 (0.042–0.115)	< 0.001
C-ACS + NLR	0.720 (0.674–0.767)	0.077 (0.041–0.112)	< 0.001
C-ACS + MLR	0.712 (0.669–0.754)	0.069 (0.027–0.107)	< 0.001
C-ACS + ELR	0.686 (0.639–0.734)	0.044(0.017–0.066)	< 0.001

△C-statistics indicated the difference in C-statistic between C-ACS models and models additionally including leukocytes, neutrophils, lymphocytes, monocytes, eosinophils, basophils, NMLR, NLR, MLR, or ELR

C-ACS Canada Acute Coronary Syndrome Risk Score, NMLR neutrophil-plus-monocyte-to-lymphocyte ratio, NLR neutrophil-to-lymphocyte ratio, MLR monocyte-to-lymphocyte ratio, ELR eosinophil-to-leukocyte ratio