Table 3.
Correlations between cytokines and adipokines with clinical variables: including disease activity index, rSLEDAI score, individual markers of renal activity or renal dysfunction and glucocorticoids doses in SLE-patients
| MIF (ng/mL) n = 196 |
Leptin (ng/mL) n = 196 |
Adiponectin (μg/mL) n = 196 |
Resistin (ng/mL) n = 188 |
|||||
|---|---|---|---|---|---|---|---|---|
| rs | p | rs | p | rs | p | rs | p | |
| Age, years | −0.21 | 0.003 | 0.04 | 0.62 | −0.13 | 0.07 | 0.03 | 0.67 |
| BMI, kg/m2 | − 0.06 | 0.36 | 0.47 | < 0.001 | −0.27 | < 0.001 | 0.21 | 0.004 |
| Disease duration, years | −0.21 | 0.004 | 0.06 | 0.38 | −0.07 | 0.35 | 0.06 | 0.42 |
| SLEDAI, score | 0.04 | 0.54 | 0.09 | 0.22 | 0.11 | 0.13 | 0.03 | 0.70 |
| rSLEDAI, score | −0.003 | 0.96 | 0.1 | 0.17 | 0.21 | 0.004 | 0.13 | 0.07 |
| MEX-SLEDAI, score | 0.02 | 0.75 | 0.1 | 0.13 | 0.16 | 0.03 | 0.04 | 0.58 |
| SLICC/ACR, score | 0.15 | 0.15 | 0.09 | 0.24 | 0.03 | 0.65 | 0.19 | 0.01 |
| Proteinuria, g/24 h | −0.02 | 0.77 | 0.18 | 0.01 | 0.19 | 0.009 | 0.26 | < 0.001 |
| Creatinine, mg | 0.27 | 0.04 | 0.12 | 0.1 | 0.16 | 0.22 | 0.18 | 0.02 |
| eGFR (mL/min/m2) | 0.11 | 0.13 | 0.17 | 0.02 | −0.15 | 0.05 | 0.01 | 0.91 |
| Creatinine clearance (mL/min) | 0.07 | 0.39 | 0.1 | 0.89 | −0.01 | 0.18 | −0.06 | 0.44 |
| GCs dose, mg/day | −0.04 | 0.63 | 0.1 | 0.15 | 0.17 | 0.02 | 0.16 | 0.03 |
rs Spearman Rank Correlation, BMI Body mass index, GCs Glucocorticoids, SLE Systemic Lupus Erythematosus, SLEDAI SLE Disease Activity Index, rSLEDAI Renal SLEDAI, MEX-SLEDAI Mexican version of SLEDAI, SLICC/ACR Systemic Lupus International Collaborating Clinics/American College of Rheumatology, eGFR Estimated glomerular filtration rate. Glucocorticoids included: prednisone or deflazacort. GCs dose were expressed as equivalent to prednisone. Spearman Rank Correlation test p < 0.05