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. 2020 Sep 28;152(11):e201912512. doi: 10.1085/jgp.201912512

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© 2020 Cely-Ortiz et al.

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Figure S3. — S2814D mice show increased [³H]ryanodine binding and SR Ca²⁺ sparks frequency. (A and B) Pseudophosphorylation of RYR2 at Ser2814 site (S2814D) significantly increases maximal density of high-affinity [³H]ryanodine binding sites (A) and the frequency of SR Ca²⁺ sparks (B). Data are expressed as mean ± SEM. n, number of animals. In B, numbers within parentheses are the number of cells.