Table 3.

Summary of known AChR subunits to be expressed in glial cells in human, rat, and mouse.

		Microglia		Astrocytes
		Subunits	Origin	Subunits	Origin
Human	nAChR	α3, α5, α7, β4	Fetal brain (Rock et al., 2008)	α7	Hippocampus and entorhinal cortex (Teaktong et al., 2003)
	mAChR	M5	Levey (1996)	M2, M3, M5	Fetal brain (Guizzetti et al., 1996)
Rat	nAChR	α7, α4, β2	Neonatal Cortex (Morioka et al., 2014) Adult brain (Martín et al., 2015)	α4, α7, β2, β3	Neonatal brain (Xiu et al., 2005)
	mAChR	M1	Adult cortex and hippocampus (Huang et al., 2016)	M2, M3, M5	Cell line 132 1N1 (Guizzetti et al., 1996)
Mouse	nAChR	α7	Cerebral cortices (Shytle et al., 2004)	α7 β4	Neonatal brain (Patel et al., 2017) The hippocampus of the adult brain (Gahring et al., 2004)
	mAChR	M1, M2, M3, M4, M5	Neonatal and adult whole brain (Pannell et al., 2016)	M1, M3	Neonatal cerebral hemisphere, mesencephalon, and medulla-pons (André et al., 1994)

This table presents the different subunits of nAChR and mAChR that have been found until today (and to the best of our knowledge) in microglia and astrocytes in humans, rat, and mice.