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. 2020 Apr 29;66(10):1142–1151. doi: 10.1097/MAT.0000000000001283

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Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the ASAIO.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 6. — Neither Impella 5.5 nor Centrimag significantly altered plasma level of von Willebrand factor antigen (vWF:Ag) while facilitating a notable decrease of its collagen binding ability (vWF:CBA) over shear exposure time. vWF:Ag and vWF:CBA were measured using in-house ELISA. Results are reported as % vWF:Ag of an internal assay standard (canine pooled plasma vWF:Ag = 100%). vWF:CBA/vWF:Ag index indicates functional activity of vWF. Data of three experiments are reported as mean ± SD, one-way repeated measures ANOVA with Dunnett’s multiple comparison test: no mark: p > 0.05 as compared with nonsheared control “0 Still.” No statistically significant difference was found between devices for vWF:Ag and vWF:CBA (two-tailed paired t-test, p > 0.05). ANOVA, analysis of variance; ELISA, enzyme-linked immunosorbent assay; SD, standard deviation.