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. 2020 Oct 25;26:e926800-1–e926800-18. doi: 10.12659/MSM.926800

Table 3.

The GO function enrichment analysis of ITGA3, ITGA5, and ITGA6 and neighbor genes in head and neck squamous cell carcinoma (HNSC).

GO Category Description Count % Log10(P) Log10(q)
GO:0031581 GO Biological Processes Hemidesmosome assembly 7 58.33 −21.18 −16.98
GO:0030198 GO Biological Processes Extracellular matrix organization 14 66.67 −20.44 −16.54
GO:0007229 GO Biological Processes Integrin-mediated signaling pathway 8 66.67 −16.26 −13.06
GO:0043589 GO Biological Processes Skin morphogenesis 3 25.00 −7.81 −5.43
GO:0001525 GO Biological Processes Angiogenesis 7 33.33 −6.34 −4.11
GO:0000904 GO Biological Processes Cell morphogenesis involved in differentiation 6 28.57 −4.48 −2.38
GO:0031623 GO Biological Processes Receptor internalization 3 14.29 −3.89 −1.85
GO:0030100 GO Biological Processes Regulation of endocytosis 3 25.00 −3.48 −1.46
GO:0043065 GO Biological Processes Positive regulation of apoptotic process 4 19.05 −2.60 −0.69
GO:0005604 GO Cellular Components Basement membrane 9 52.94 −17.36 −14.07
GO:0008305 GO Cellular Components Integrin complex 7 41.18 −16.27 −13.29
GO:0030056 GO Cellular Components Hemidesmosome 4 23.53 −10.93 −8.90
GO:0005581 GO Cellular Components Collagen trimer 3 17.65 −4.53 −2.82
GO:0031091 GO Cellular Components Platelet alpha granule 3 17.65 −4.47 −2.79
GO:0048471 GO Cellular Components Perinuclear region of cytoplasm 5 21.74 −3.28 −1.73
GO:0005178 GO molecular functions Integrin binding 13 65.00 −24.58 −20.92
GO:0050840 GO molecular functions Extracellular matrix binding 7 58.33 −15.78 −12.81
GO:0038132 GO molecular functions Neuregulin binding 3 25.00 −9.03 −6.54
GO:0005201 GO molecular functions Extracellular matrix structural constituent 6 30.00 −8.48 −6.02
GO:1901681 GO molecular functions Sulfur compound binding 3 15.00 −2.94 −0.99
GO:0045296 GO molecular functions Cadherin binding 3 15.00 −2.61 −0.68