Table 6.
Association of CCHCR1 single-nucleotide variations in UK Biobank with and without human leukocyte antigen adjustment
| SNV | UKBB T1D | UKBB T1D adj HLA type | UKBB T2D | UKBB T2D adj HLA type | ||||
|---|---|---|---|---|---|---|---|---|
| Estimate | P | Estimate | P | Estimate | P | Estimate | P | |
| rs3130453_T | 0.342 | 1.46 × 10–18 | 0.0244 | .563 | 0.0344 | .00331 | 0.0352 | .00431 |
| rs3131012_C | 0.282 | 9.45 × 10–13 | 0.0164 | .699 | 0.0575 | 1.09 × 10–06 | 0.0604 | 8.60 × 10–07 |
Abbreviations: adj, adjusted; CCHCR1, coiled-coil α-helical rod protein 1; HLA, human leukocyte antigen; SNV, single-nucleotide variation; T1D, type 1 diabetes; T2D, type 2 diabetes; UKBB, UK Biobank.