Table 1.
Clinical Characteristics of Patients with Congenital Adrenal Hyperplasia Compared With Controlsa
| CAH Patients (n = 36) | Controls (n = 27) | P-Value | |
|---|---|---|---|
| Age (years) | 28.5 [22.3–35.8] | 28.0 [23.0–31.0] | 0.498 |
| BMI (kg/m2) | 29.4 [22.6–35.5] | 24.5 [21.6–28.4] | 0.013 |
| Marital Status (# married, %) | 9 (25%) | 4 (14.8%) | 0.323 |
| Race (#, %) | |||
| White | 28 (77.8%) | 23 (85.2%) | 0.218 |
| Black or African American | 3 (8.3%) | 4 (14.8%) | |
| Multiple Races | 1 (2.8%) | 0 | |
| Unknown | 4 (11.1%) | 0 | |
| Ethnicity (#, %) | |||
| Not Latino or Hispanic | 29 (80.5%) | 26 (96.3%) | 0.172 |
| Latino or Hispanic | 6 (16.7%) | 1 (3.7%) | |
| Unknown | 1 (2.8%) | 0 | |
| Gender a (#, %) | |||
| Female | 34 (94.4%) | 26 (96.3%) | |
| Male | 1 (2.8%) | 0 | 0.671 |
| Other | 1 (2.8%) | 1 (3.7%) | |
| Disease Control (# in control, %) b | 28 (77.8%) | N/A | |
| Sexual Preference (#, %) | |||
| Men | 22 (61.1%) | 26 (96.3%) | 0.013 |
| Women | 6 (16.7%) | 0 | |
| Both | 6 (16.7%) | 1 (3.7%) | |
| Neither/Asexual | 2 (5.5%) | 0 | |
| Sexual Activity | |||
| Ever Sexually Active (#, %) | 26 (72.2%) | 27 (100%) | 0.003 |
| # of Partners (#) | 1 [0–4] c | 8 [4–12] | 0.013 |
| Age of Menarche (years) | 13 [12–15] | 12 [12–13] | 0.067 |
| Regular Menses (#, %) | 15 (41.7%) | 24 (88.9%) | <0.001 |
| Pregnancy in Sexually Active (#, %) | 6 (23.1%) | 4 (14.8%) | 0.442 |
| Contraception Use in Sexually Active (#, %) | |||
| Past | 22 (84.6%) | 26 (96.3%) | 0.146 |
| Present | 12 (46.2%) | 22 (81.5%) | 0.007 |
| Hormonal | 21 (80.8%) | 25 (92.6%) | 0.204 |
Median [interquartile range] unless otherwise specified.
a Controls were age-, race-, and marital status–matched.
b Good disease control defined as androstenedione within reference range.
c n = 35 patients responded.