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. 2020 Oct 23;27(1):1397–1411. doi: 10.1080/10717544.2020.1827085

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — (A) Ex vivo imaging of tumor and organs excised from BALB/c nude mice. Tumor and major organs were collected from the mice at 6 h post-injection, and then the fluorescence signals were detected. (B) Quantitative analysis of the fluorescence intensity of ex vivo images of tumors. (C) Quantitative analysis of the fluorescence intensity of ex vivo images of organs. In vivo anti-tumor efficacy of various nanoparticle formulations against NCI-H460 tumor in mice. (D) Imaging of the tumors collected from mice at the termination of treatment. (E) Tumor growth curve after injection of different nanoparticles for a total five doses. *p < 0.05, **p < 0.01, compared to PTX/siRNA/FALS group. (F) VEGF expression level in tumor was analyzed by Western Blotting. (G) Quantitative analysis of the Western blot bands. The VEGF expression level was normalized to β-actin and analyzed. Data are shown as mean ± SD.