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. 2020 Oct 26;27(1):1438–1451. doi: 10.1080/10717544.2020.1831104

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — (a) Growth factors binding with GAGs (Hachim et al., 2019). (b) the chemical structure of hyaluronate-epidermal growth factor (HA-EGF) conjugates; the fluorescence graphs of the degradation behavior of EGF and HA-EGF conjugate in HA films after topical application of FITC-labelled samples on wounded tissues (Niu et al., 2019). (c) HB-EGF released from sHA1-AC-containing hydrogels promotes epidermal tip formation and the results were measured by Masson-Goldner Trichrome staining. Bars: 500 μm; 100 μm (insets). The combined tip lengths of both wound sites were shown (n = 3 with 3–4 sections per condition *p < .05, **p < .01, ***p < .005, ****p < .001) (Thönes et al., 2019).