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ctDNA as a biomarker for neoplastic detection, predictive diagnostics and prognosis
| Procedure | Application | Reference |
|---|---|---|
| Diagnosis | Early detection | [94, 133, 134, 136, 137] |
| Prediction | Molecular heterogeneity | [141] |
| Tumour dynamic assessment | [128, 129, 142] | |
| Determination of early treatment response | [138, 139] | |
| Acquired resistance | [138, 140] | |
| Prognosis | Detection of marginal disease residues | [143–146] |
| Survival and recurrence rate | [148] | |
| Tumour load determination | [149] |
