Tab. II.
Safety profile.
| Drug-related adverse events: incidence and costs | |||||
|---|---|---|---|---|---|
| Drug-related adverse events | Men who have sex with other men [3, 4] | Serodiscordant couples [3, 4] | Injection drug users [3-5] | Cost for the NHS | Cost for citizen |
| Nausea | 8% | 8% | 8% | € 52.74 | € 22.15 |
| Vomiting | 2% | 2% | 5% | € 52.74 | € 22.15 |
| Diarrhea | 4% | 4% | 11% | € 1,822.21 | € 306.26 |
| Abdominal pain | 7% | 7% | 9% | € 50.00 | € 21.00 |
| Bone disease | 2% | 2% | 2% | € 661.44 | € 527.40 |
| Creatinine Increase | 18% | 10% | 7% | € 1,474.61 | € 549.73 |
| Headache | 8% | 8% | 8% | € 20.07 | € 8.43 |
| Rash | 8% | 8% | 8% | € 760.13 | € 264.72 |
| Other sexually transmitted/blood borne infections | % PREP [3, 4] | % NO PREP [2] | Cost for the NHS | Cost for citizen | |
| HCV | 1% | 2% | € 8,545.97 | € 950.89 | |
| Syphilis | 10% | 9% | € 117.75 | € 49.55 | |
| Chlamydia | 27% | 22% | € 76.00 | € 31.98 | |
| Gonorrhea | 38% | 37% | € 88.67 | € 37.31 | |
| Rectal or vaginal Infection | 36% | 32% | € 267.72 | € 112.66 | |