Table 1.

Phenotypes.

Phenotype	Abbreviation	n	Min	Max	Mean	SD
Endophenotypes
Intermediates in cholesterol biosynthesis
Squalene	Sq	245	0.70	17.30	4.96	3.69
Lanosterol	Lan	284	1.43	5.89	3.42	0.91
Lathosterol	Lat	299	13.06	96.99	49.85	17.15
Desmosterol	Des	300	22.33	123.63	68.35	20.06
Sum of intermediates	Sint	300	36.15	222.51	129.05	35.00
Phytosterols
Betasitosterol	Bsit	297	45.36	470.17	186.60	96.30
Campesterol	Cste	288	106.68	862.77	392.42	158.37
Stigmasterol	Stig	249	0.16	2.56	1.14	0.48
Sum of phytosterols	Sphy	290	187.96	1253.79	577.60	232.74
Microbiota-derived sterols
Coprostanol	Csta	298	1.95	31.12	13.66	6.35
Epicoprostanol	Esta	276	0.23	5.41	2.23	1.11
Sum of microbiota-derived sterols	Sste	303	2.17	35.01	15.84	7.28
End-point phenotypes
LDL-Cholesterol	LDL-C	296	30.82	86.53	57.70	10.67
HDL-Cholesterol	HDL-C	317	13.00	57.00	36.19	7.92
Total Cholesterol	TC	297	67.78	137.84	100.88	13.88
Triglycerides	TG	295	42.57	200.12	119.68	31.02

All endophenotypes were measured in µg/dl. End-point phenotypes were measured in mg/dl.

SD = standard deviation of the mean.