Fig. 5. Evaluation of treatment efficacy by biofilm-like L. paracasei ATCC334 encapsulated in pectin beads in DSS-induced colitis mice.

The results presented are representative of 8 mice from each group. Asterisks indicate statistically significant differences from the DSS-induced colitic group (*P < 0.05), (Kruskal–Wallis test). a Changes in mouse body weight during and after DSS administration. The percent change in body weight was calculated by using the weight on day 5 (the day of DSS initiation) as the reference. b Clinical assessment of DSS-induced colitis. Disease Activity Index (DAI) was scored from each mouse for weight loss, stool consistency, and bleeding. c Histological sections of H&E-stained colon of representative mice from each group (tissue damage is shown by arrows) (scale bars, 30 μm).