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. 2020 Oct 28;9(10):97. doi: 10.1038/s41389-020-00283-x

Fig. 6. FOXP3 inhibited tumor growth in the tumor model of nude mice.

Fig. 6

a The representative image for tumor growth in nude mice and the detection of relevant proteins by IHC staining. b Subcutaneous tumor growth curve of Hep3B-FOXP3 in nude mice was compared with the control. The tumor volume in the FOXP3 group was much smaller than the control (P = 0.001). c The Pearson coefficient analysis of the correlation between FOXP3 and 4 other molecules: Ki-67 (-0.86), c-Myc (-0.87), Smad2/3 (0.89) and p-Smad3 (0.93), P < 0.05. d The expression of FOXP3 was negatively correlated with c-Myc in HCC tissues (r = −0.78, P < 0.05).