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. 2020 Oct 28;11(10):928. doi: 10.1038/s41419-020-03133-1

Fig. 6. Antitumor effects in an orthotopic implantation glioma model.

Fig. 6

C57BL/6 mice were inoculated with 1 × 103 Gl261 cells by intracranial implantation and treated with NS, vehicle, Dox/M, α-m/M or α-m-Dox/M intravenously once every three days. a Optical in vivo imaging (n = 6). b H&E staining of the brain. c Enlargement of the corresponding position of the tumor. d Survival curves of the different groups (n = 10). e Body weights. Data are representative of at least three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001; ANOVA, Student’s t-test and Kaplan–Meier survival analysis (log-rank test).