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. 2020 Oct 28;10:18529. doi: 10.1038/s41598-020-75152-z

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Steps to compute the location of the onset of each cardiac pulse for a 10-s PPGi time series: (a) Input PPGi waveform. (b) Slope sum function (SSF). (c) Boxed Slope Sum Function (BSSF), scaled to match each pulse in the SSF function. (d) The adaptive threshold applied to the uBSSF signal. (e) The detected beat onsets.