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. 2020 Oct 28;11(10):926. doi: 10.1038/s41419-020-03108-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — The HepG2 cells were injected subcutaneously into nude mice and treated with ZJQ-24 (20 mg/kg), ZJQ-24 (40 mg/kg), ZJQ-24 (60 mg/kg) every two days for 3 weeks. A Tumor volumes was monitored over 21 day period, presented as mean ± SD. B The bodyweight of HepG2 xenograft mouse. C H&E staining and immunohistochemical staining were performed to analyze the number of tumor cells and the expression levels of Ki67 in tumor tissues.