Table 1. Overview of programmatic strategies for identifying households likely to have asymptomatic and/or subpatent infections.
Strategy | Index Household | Control Population | Case Definition | Adapted Case Definitions for DHS Data |
---|---|---|---|---|
RACD | Residence of individuals with confirmed infections detected within health facilities |
|
All individuals residing in the index household, not including the index case in the case of RACD | Any other child of the household is positive for malaria by RDT/microscopy and has sought antimalarial treatment |
MSAT | Symptomatic case (fever and RDT/microscopy positive) detected in the community as part of an active campaign | Households that have been randomly selected in the same community as the index household as part of a cross-sectional study | Any other child of the household positive by RDT/microscopy and has had a fever during the past 2 weeks | |
MTAT | Any infected individual (RDT/microscopy positive) detected in the community as part of an active campaign | Any other child of the household is malaria positive by RDT/microscopy |
For this analysis, we have defined an index household, and index and control populations for each strategy. Infections in index and control populations have been confirmed using RDT/microscopy in the DHS studies and molecular methods in the meta-analysis.
Abbreviations: DHS, demographic health survey; MSAT, Mass Screen and Treat; MTAT, Mass Test and Treat; RACD, Reactive Case Detection; RDT, rapid diagnostic test