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. 2020 Oct 29;17(10):e1003370. doi: 10.1371/journal.pmed.1003370

Table 1. Overview of programmatic strategies for identifying households likely to have asymptomatic and/or subpatent infections.

Strategy Index Household Control Population Case Definition Adapted Case Definitions for DHS Data
RACD Residence of individuals with confirmed infections detected within health facilities
  1. Households neighbouring index households with the screening radius defined according to the study

  2. Households that have been randomly selected in the same community as the index household, as part of a cross-sectional study

All individuals residing in the index household, not including the index case in the case of RACD Any other child of the household is positive for malaria by RDT/microscopy and has sought antimalarial treatment
MSAT Symptomatic case (fever and RDT/microscopy positive) detected in the community as part of an active campaign Households that have been randomly selected in the same community as the index household as part of a cross-sectional study Any other child of the household positive by RDT/microscopy and has had a fever during the past 2 weeks
MTAT Any infected individual (RDT/microscopy positive) detected in the community as part of an active campaign Any other child of the household is malaria positive by RDT/microscopy

For this analysis, we have defined an index household, and index and control populations for each strategy. Infections in index and control populations have been confirmed using RDT/microscopy in the DHS studies and molecular methods in the meta-analysis.

Abbreviations: DHS, demographic health survey; MSAT, Mass Screen and Treat; MTAT, Mass Test and Treat; RACD, Reactive Case Detection; RDT, rapid diagnostic test