Table 3. Results of the linear regression modelling for each of the 3 strategies assessed, including the neighbor and community controls for the RACD strategy.

Strategy	Intercept	Slope, OR (95% CI)	P Value	N Studies	I2 (%)
RACD—Community	1.04	1.78 (1.01–3.12)	0.058	6	61.7
RACD—Neighbors	0.81	1.46 (1.13–1.88)	0.009	11	59.1
MSAT	0.80	2.34 (1.73–3.17)	0.001	8	96.2
MTAT	1.72	1.68 (0.90–3.13)	0.097	17	95.5

Log linear trends were estimating according to increasing OR against decreasing malaria prevalence. The results are presented on the OR scale for ease of interpretation. PCR method or continental region didn’t have an impact on the estimates, but sample sizes were too small to assess this formally. Results suggest an increase in OR or malaria infections clustering as PCR prevalence decreases across all strategies. The number of studies included in the pooled analysis as well as the assessment of heterogeneity within the strata (I²) are also presented.

Abbreviations: MSAT, Mass Screen and Treat; MTAT, Mass Test and Treat; OR, odds ratio; RACD, Reactive Case Detection