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. 2020 Oct 29;15(10):e0240230. doi: 10.1371/journal.pone.0240230

Table 3. The functional annotation and enrichment of modules genes.

Module Term Count PValue FDR Genes
module1 GO:0000922~spindle pole(CC) 4 2.42E-05 2.13E-02 CCNB1, KIF11, MAD2L1, PRC1
GO:0051301~cell division(BP) 5 3.53E-05 3.95E-02 CCNB1, KIF2C, KIF11, MAD2L1, CCNB2
GO:0015630~microtubule cytoskeleton(CC) 4 4.80E-05 4.22E-02 KIF2C, CCNB2, PRC1, MCM2
module2 hsa05200:Pathways in cancer(KEGG) 8 7.41E-05 8.34E-02 ADCY1, CDKN2A, BCR, CDKN2B, RXRA, BCL2, GNB5, GNAS
GO:0071456~cellular response to hypoxia(BP) 4 2.58E-04 3.71E-01 BCL2, PPARGC1A, SLC9A1, PCK1
GO:0042493~response to drug(BP) 5 5.95E-04 8.55E-01 ADCY1, BCL2, GNAS, PPARGC1A, SLC9A1
module3 hsa04310:Wnt signaling pathway(KEGG) 7 4.55E-09 3.09E-06 WNT5A, DKK2, FRAT1, FRAT2, WIF1, LRP5, APC
GO:1904886~beta-catenin destruction complex disassembly(BP) 4 2.33E-07 2.95E-04 FRAT1, FRAT2, LRP5, APC
GO:0016055~Wnt signaling pathway(BP) 5 2.97E-06 3.76E-03 WNT5A, DKK2, WIF1, LRP5, APC