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. Author manuscript; available in PMC: 2020 Oct 29.
Published in final edited form as: Clin Cancer Res. 2017 Mar 22;23(15):4163–4169. doi: 10.1158/1078-0432.CCR-16-2658

Figure 3. Antitumor activity in metastatic lesions.

Figure 3

(A) Waterfall analysis on a lesion-by-lesion basis. Best change in lesion size is defined as the maximal reduction or minimal increase in sum of longest dimensions of target lesions relative to pretreatment assessment. 25/28 patients had measurable tumors at baseline and at least one post-treatment evaluation. Letters above or below bar denotes location of the lesion: V = liver; L = lung; N = lymph node; A = adrenal gland; P = primary tumor; B = bone. (B) Metastatic lung lesion of an endometrial cancer patient at baseline and after 8 doses of 625mg ONC201.