Table 1.
Dose escalation cohorts (n=10) | Dose expansion (n=18) | |
---|---|---|
Male | 5 | 8 |
Female | 5 | 10 |
Age (years)* | 66.8 (47–80) | 60.1 (26–90) |
Weight (kg)* | 76 (47.7–123) | 73 (47.7–118.9) |
Cycles/Doses of ONC201* | 3.2 (1–4) | 3.3 (1–14) |
Prior therapies* | 5.5 (1–10) | 6.2 (3–18) |
Prior radiation | 5 | 12 |
Prior surgeries | 9 | 13 |
indicate the mean with the range in parentheses.