Table 1.
GEO Datasets included in systematic review
| GEO Accession | PMID | n | Platform | Tissue | Outcome | Initial Lambda | Recalculated Lambda | Permutation Median Lambda (95% CI) | Bonferroni Δ | Source of Initial Lambda |
|---|---|---|---|---|---|---|---|---|---|---|
| GSE56046 | 25404168 | 1202 | 450 k | Blood | age | 3.12 | - | - | MWAS of processed data | |
| GSE87571 | 23826282 | 732 | 450 k | Blood | age | 17.68 | 7.69 | 0.97 (0.86–1.38) | 92,591 | Calculated from summary statistics |
| GSE72774 | 26655927 | 508 | 450 k | Blood (all samples) | age | 5.48 | - | - | MWAS of processed data | |
| Blood (controls only) | age | 2.16 | - | - | ||||||
| GSE72778 | 27479945 | 475 | 450 k | Brain (meta-analysis) | age | 7.30 | - | - | Reported in manuscript | |
| Brain (frontal lobe) | age | 3.50 | - | - | ||||||
| Brain (parietal lobe) | age | 3.00 | - | - | ||||||
| Brain (occipital lobe) | age | 2.20 | - | - | ||||||
| GSE55763 | 25853392 | 2711 | 450 k | Blood | Case-control | 1.00 | - | - | Reported in manuscript | |
| GSE84727 | 27572077 | 847 | 450 k | Blood | Case-control | 1.53 | - | - | MWAS of processed data | |
| GSE42861 | 23334450 | 689 | 450 k | Blood | Case-control | 15.17 | 1.14 | 1.00 (0.96–1.08) | 57,805 | MWAS of processed data |
| GSE74193 | 26619358 | 675 | 450 k | Brain | Case-control | 64.65 | 4.37 | 0.98 (0.78–1.35) | 178,241 | Calculated from summary statistics |
| GSE80417 | 27572077 | 675 | 450 k | Blood | Case-control | 1.32 | - | - | MWAS of processed data | |
| GSE111629 | 28851441 | 572 | 450 k | Blood | Case-control | 1.77 | 1.01 | 1.00 (0.93–1.11) | 7 | MWAS of processed data |
| GSE87648 | 27886173 | 384 | 450 k | Blood | Case-control | 1.54 | 1.13 | 1.01 (0.82–1.35) | −202 | MWAS of processed data |
| GSE100264 | 29269866 | 386 | 450 k | Blood | Ordinal (drug use) | 1.08 | - | - | Reported in manuscript |