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CD28, CTLA4, ICOS, CD80, and CD86 methylation in isolated immune cells and HNSCC cell lines. Shown are methylation levels in isolated immune cell subsets (N = 28) from healthy donors, and in HPV-negative (N = 34) and HPV-positive (N = 5) HNSCC cell lines exemplarily at three CpGs targeting CD28, three CpGs targeting CTLA4, two CpGs targeting ICOS, two CpGs targeting CD80 and four CpGs targeting CD86. Red bars indicate median methylation levels
