Table 1. Patients’ demographic characteristics.
| Cont | CS | CHB | P value | |
|---|---|---|---|---|
| Liver samples | ||||
| Subject no. | 8 | 31 | 15 | |
| Male sex | 5(63%) | 19(61%) | 11(73%) | 0.7170 |
| Age(y) | 62(59–66) | 50(43–62) | 52(48–55) | 0.0543 |
| History of S. japonicum/hepatitis B virus infection | ||||
| <10 years | 0(0%) | 2(7%) | 3(20%) | |
| 10–20 years | 0(0%) | 14(45%) | 4(27%) | |
| >20 years | 0(0%) | 15(48%) | 8(53%) | |
| Stage of fibrosis | ||||
| S0 | 8(100%) | 0(0%) | 0(0%) | |
| S1 | 0(0%) | 6(19%) | 0(0%) | |
| S2 | 0(0%) | 5(16%) | 0(0%) | |
| S3 | 0(0%) | 8(26%) | 0(0%) | |
| S4 | 0(0%) | 12(39%) | 15(100%) | |
| Splenectomy(S4%) | 0(0%) | 9(75%) | 8(53%) | 0.0040 |
| Ascites(S4%) | 0(0%) | 5(42%) | 4(27%) | 0.1120 |
| EGVB(S4%) | 0(0%) | 4(33%) | 6(40%) | 0.1170 |
| Spleen samples | ||||
| Subject no. | 9 | 12 | 13 | |
| Male sex | 5(56%) | 7(58%) | 7(54%) | 0.9750 |
| Age(y) | 53(52–64) | 51(43–65) | 51(45–56) | 0.3397 |
| History of S. japonicum/hepatitis B virus infection | ||||
| <10 years | 0(0%) | 0(0%) | 4(31%) | |
| 10–20 years | 0(0%) | 5(42%) | 6(46%) | |
| >20 years | 0(0%) | 7(58%) | 3(23%) | |
| Ascites | 4(44%) | 5(42%) | 3(23%) | 0.4980 |
| EGVB | 0(0%) | 6(50%) | 3(23%) | 0.0350 |
For continuous variables, results are expressed as median and interquartile range. Categorical variables are summarized by using percentages. Boldface indicates P <0.05. S4%, the percentage of S4 population; Cont, control; CS, chronic schistosomiasis; CHB, chronic hepatitis B; EGVB: esophagealgastricvariceal bleeding