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. 2020 Oct 9;46(6):2007–2018. doi: 10.3892/ijmm.2020.4750

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Copyright: © Zhao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Upregulation of hepatoma-derived growth factor (HDGF) reverses the effects of long intergenic non-coding RNA (LINC)01232 silencing in esophageal squamous cell carcinoma (ESCC) cells. (A) Western blot analysis was used to analyze the efficiency of pcDNA3.1-HDGF transfection in Eca109 and KYSE150 cells. (B-E) The pcDNA3.1-HDGF or pcDNA3.1 plasmid was introduced into Eca109 and KYSE150 cells in the presence of small interfering RNA specific for LINC01232 (si-LINC01232). Cell proliferation, apoptosis, and migration and invasion were assessed by CCK-8 assay, flow cytometry, and migration and invasion assays, respectively. ^*P<0.05 and ^**P<0.01 vs. respective control.