Figure 6.

Loss of long intergenic non-coding RNA (LINC)01232 suppresses tumor growth in vivo. (A) Images of excised tumor xenografts. (B) Plots of tumor xenograft growth according to tumor volume, which was measured every 5 days. (C) Comparison of tumor weights obtained from nude mice euthanized at the end of day 30. (D and E) Analysis of LINC01232 and microRNA (miR)-654-3p expression in tumor xenografts was performed by reverse transcription-quantitative polymerase chain reaction. (F) HDGF protein expression was measured by western blot analysis in total protein isolated from tumor xenografts in the groups that were injected with ESCC cells treated with short hairpin RNA (sh) specific for LINC01232 or a negative control (sh-ctrl). ^**P<0.01 vs. sh-ctrl.