Table 3.
Estimates from the logistic regression models studying the effect of Ln-RHI/Ln-sE-selectin and age group on the probability of infection
| Variable | Coefficient | Standard error | p value | OR | 95% CI for OR | ROC AUC; p value | Se/Sp | PPV/NPV | Threshold for predicted probabilities (Se/Sp) | |
|---|---|---|---|---|---|---|---|---|---|---|
| Model A | Ln_RHI | -1.368 | 0.605 | 0.024 | 0.255 | 0.078 - 0.833 | 0.726; p < 0 .01 | 75%/71% | 75%/71% | 0.55 (86%/54%) |
| Age | ||||||||||
| < 60 y.o. | Reference | - | - | - | - | |||||
| ≥ 60 y.o. | -1.629 | 0.538 | 0.002 | 0.196 | 0.068 - 0.563 | |||||
| Model B | Ln_sE-selectin | 1.308 | 0.504 | 0.009 | 3.698 | 1.398 - 9.931 | 0.780; p < 0.01 | 94%/20% | 81%/50% | 0.52 (59%/93%) |
| Age | ||||||||||
| < 60 y.o. | Reference | - | - | - | - | |||||
| ≥ 60 y.o. | -1.412 | 0.669 | 0.035 | 0.244 | 0.066 - 0.904 |
AUC - area under curve; CI - confidence interval; Ln - natural logarithm; OR - odds ratio; PPV - positive predictive value; NPV - negative predictive value; RHI - reactive hyperemia index; ROC - receiver operator curve; Se - sensitivity; Sp - specificity.