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Excipients used in marketed inhaled protein formulations
| Product | Device type | Active Pharmaceutical Ingredient (API) | Excipients |
|---|---|---|---|
| Pulmozyme® (approved 1993) | Jet nebuliser | Dornase alfa (DNase I) | sodium chloride, calcium chloride dihydrate |
| Exubera® (approved 2006, discontinued 2007) | DPI | Insulin human | mannitol, sodium citrate, glycine, sodium hydroxide |
| Afrezza® (approved 2014) | DPI | Insulin human | fumaryl diketopiperazine, polysorbate 80 |
