Table 2.
Prediction Performance Using Cross Validation and Independent Testing Dataset
| Dataset | Testing Method | Sn (%) | Sp (%) | ACC (%) | MCC | AUC |
|---|---|---|---|---|---|---|
| Full transcript | cross validation | 87.59 | 89.04 | 88.32 | 0.767 | 0.956 |
| independent test set | 87.90 | 88.80 | 88.35 | 0.767 | 0.956 | |
| Mature mRNA | cross validation | 88.64 | 91.18 | 89.91 | 0.798 | 0.956 |
| independent test set | 87.44 | 91.95 | 89.70 | 0.795 | 0.954 |
80% of experimentally validated m5U sites were used for training, while its performance was evaluated by the remaining 20% as independent testing data.