FIGURE 5.

hsa_circ_0023642 is a sponge of miR‐223a‐3p. A, The Venn diagram shows the intersection of miRNA lists. B, RIP experiments were performed using an antibody against AGO2 with extracts from MKN‐45 and SCG7901 cells. C, qRT‐PCR results showed that hsa_circ_0023642 could be specifically enriched by hsa_circ_0023642 probe. D, The relative expression levels of miR‐223‐3p was detected by qRT‐PCR inMKN‐45 and SCG7901 cell lysates. E, The expression of hsa_circ_0023642 and miR‐223‐3p are inversely correlated in GC tissues. F, The Venn diagram shows the intersection of mRNAs lists between StarBase and Targetscan. G, The mRNA levels of FBXW7, RHOB, LELP1 and PTS in MKN45 cells with knockdown or overexpression of hsa_circ_0023642 was determined by qRT‐PCR. H, Expression of FBXW7 and hsa_circ_0023642 are positively correlated in GC tissues (R ² = 0.5572, P < .0001, n = 46)