Table 3.
Risk factors associated with COVID‐19 in‐hospital death
| Univariable OR(95%CI) | P value | Multivariable OR(95%CI) | P value | |
|---|---|---|---|---|
| Age, y (vs ≤ 61) | 4.02 (1.04‐15.41) | .0423 | ||
| NEU,×109/L (vs ≤ 4.47) | 19.73 (2.46‐158.21) | .0050 | 58.35 (2.16‐1571.69) | .0155 |
| LYM,×109/L (vs > 0.55) | 6.34 (2.06‐19.47) | .0012 | ||
| PT, s (vs ≤ 14.7) | 15.78 (4.00‐62.17) | .0001 | ||
| APTT, s (vs >40.2) | 6.09 (1.78‐20.77) | .0039 | ||
| D‐dimer, μg/mL (vs ≤ 2.35) | 10.25 (3.08‐34.00) | .0001 | ||
| hs‐CRP, mg/L (vs ≤ 86.7) | 13.66 (3.83‐48.69) | .0001 | 14.90 (1.29‐171.10) | .0300 |
| IL‐2R,U/mL (vs ≤ 867) | 7.98 (2.08‐30.60) | .0024 | ||
| Interleukin‐6, pg/mL (vs ≤ 81.98) | 9.57 (2.81‐32.55) | .0003 | ||
| Interleukin‐8, pg/mL (vs ≤ 46.4) | 5.25 (1.71‐16.07) | .0036 | ||
| Interleukin‐10, pg/mL (vs ≤ 8.6) | 4.53 (1.49‐13.80) | .0077 | ||
| hs‐cTnI, pg/mL (vs ≤18.9) | 8.43 (2.62‐27.15) | .0003 | ||
| NT‐proBNP, pg/mL (vs ≤ 570) | 5.12 (1.70‐15.42) | .0037 | ||
| Procalcitonin, pg/mL (vs ≤ 0.09) | 15.27 (4.24‐54.99) | .0001 | ||
| CK, U/L (vs ≤101) | 18.27 (5.08‐65.69) | <.0001 | 161.62 (6.45‐4045.20) | .0020 |
| LDH, U/L (vs ≤ 450) | 5.39 (1.75‐16.56) | .0032 | ||
| BUN, mmol/L (vs ≤ 6.7) | 10.03 (3.08‐32.59) | .0001 | 11.18 (1.36‐91.62) | .0244 |
| GFR, mL/min/1.73 m2 (vs > 63.1) | 6.40 (1.77‐23.11) | .0046 |
Abbreviations: APTT, activated partial thromboplastin time; BUN, blood urea nitrogen; CK, creatine kinase; COVID‐19, coronavirus disease 2019; GFR, glomerular filtration rate; hs‐CRP, hypersensitivity C‐reactive protein; hs‐cTnI, hypersensitive cardiac troponin I; IL‐2R, interleukin‐2 receptor; LDH, lactate dehydrogenase; LYM, lymphocyte count; NEU, neutrophil count; NT‐proBNP, N‐terminal pro‐brain natriuretic peptide; OR (95%CI), odds ratio(95% confidence interval); PT, prothrombin time; WBC, white blood cell count.
OR and P values were calculated by logistic regression.