Table 2.

Current or recent clinical studies involving calciphylaxis

Title	ClinicalTrials.gov identifier	Study design	Most recent status of study
A phase 3 clinical trial of intravenous sodium thiosulfate in acute calciphylaxis patients (CALISTA)	NCT03150420	Interventional 111 participants	Terminated (inability to accrue subjects that met the exclusion criterion “any prior (within the past 30 days) or current sodium thiosulfate treatment”)
The early administration of sodium thiosulfate should help to reduce the mortality of dialysis patients with calciphylaxis, from a national cohort	NCT03146793	Observational 600 participants	Recruiting
Observational follow-up to ST-001 calciphylaxis pain treatment with sodium thiosulfate (OF-CALISTA)	NCT03319914	Observational 5 participants	Terminated (subjects did not receive Hope Pharmaceuticals’ sodium thiosulfate injection)
Efficacy of lanthanum carbonate in calciphylaxis	NCT01289626	Interventional 12 participants	Completed May 2013
Phase 2 study with SNF472 in calciphylaxis patients	NCT02790073	Interventional 14 participants	Completed November 2017
Phase 3 study of SNF472 for calciphylaxis (Calciphyx)	NCT04195906	Interventional 66 participants	Recruiting
European Calciphylaxis Registry Network (EuCalNet)	NCT02635373	Observational (patient registry) 1000 participants	Recruiting
Partners Calciphylaxis Biobank (PCB)	NCT03032835	Observational 300 participants	Recruiting
Cacliphylaxis: population, risk factors, diagnostic practice, therapeutic and outcome (CalciWest)	NCT02854046	Observational 225 participants planned	Not yet recruiting