Table 1.

Characteristics of 16 non-duplicate bla_VIM-positive clinical Enterobacteriaceae and four related environmental isolates.

Patient	Species	Source	Date	Travel	Epi Risk*	Enzyme	Isolate	ST†
1	E. hormaechei	Rectal	Sep-12	Croatia (H)	Yes	VIM-1	Eho-1	92
2	E. hormaechei	Urine	Jul-11	None	No	VIM-1	Eho-2‡	93
3	E. hormaechei	Urine	Aug-11	None	No	VIM-1	Eho-3‡	93
4	E. hormaechei	Urine	Feb-12	None	No	VIM-1	Eho-4‡	93
5	E. hormaechei	Urine	Jun-12	None	No	VIM-1	Eho-5‡	93
6	E. hormaechei	Rectal	Feb-14	None	No	VIM-1	Eho-6§	269
7	E. hormaechei	Urine	Jul-14	None	Yes (OB)&	VIM-1	Eho-7§	269
8	E. hormaechei	Dialysis fluid	Jun-15	None	Yes (OB)	VIM-1	Eho-8§	269
9	E. hormaechei	Dialysis fluid	Sep-15	None	Yes (OB)	VIM-1	Eho-9§	269
10	E. hormaechei	Rectal	Jan-16	None	Yes (OB)	VIM-1	Eho-10§	269
11	E. hormaechei	Rectal	Jan-16	None	Yes (OB)	VIM-1	Eho-11§	269
12	C. freundii	Sputum	Dec-12	Portugal (H)	Yes	VIM-2	Cfr-12	129
13a	C. freundii	Rectal	Dec-15	None	No	VIM-1	Cfr-13a	New
13b	K. pneumoniae	Rectal	Dec-15			VIM-1	Kpn-13b	17
14	K. pneumoniae	Rectal	Sep-14	Egypt (H)	Yes	VIM-1	Kpn-14	376
15	E. coli	Rectal	Nov-15	Europe	No	VIM-1	Eco-15	131
E1	E. hormaechei	Environment	Aug-15	NA	NA	VIM-1	Eho-E1‡	93
E2	E. hormaechei	Environment	Aug-15	NA	NA	VIM-1	Eho-E2§	269
E3	E. hormaechei	Environment	Aug-15	NA	NA	VIM-1	Eho-E3	93
E4	E. hormaechei	Environment	Aug-15	NA	NA	VIM-1	Eho-E4	93

H hospital, Epi epidemiologic, ST sequence type, VIM Verona integron-encoded metallo-β-lactamase, OB outbreak.

*Hospital admission outside of North America OR spatiotemporal exposure to patient with highly-related isolate.

^†ST, Sequence types, determined by multilocus sequence typing.

^&Hospital outbreak with patient 6 as first case identified, and patients #7–11 exposed to contaminated shower drains on same hospital unit (17).

^‡Cluster I.

^§Cluster II.