Table 4.
Associations of relevant factors with 30-day mortality in (a) male patients and (b) female patients.
| Univariable | Multivariable | |||||
|---|---|---|---|---|---|---|
| OR | 95%CI | p value | aOR | 95%CI | p value | |
| a | ||||||
| Male patients | ||||||
| Age (per year) | 1.04 | 1.02–1.05 | < 0.001 | 1.03 | 1.01–1.05 | 0.02 |
| SOFA (per point) | 1.18 | 1.16–1.20 | < 0.001 | 1.11 | 1.08–1.13 | < 0.001 |
| Frailty (per CFS point) | 1.21 | 1.16–1.25 | < 0.001 | 1.13 | 1.09–1.18 | < 0.001 |
| Vasoactive drug (yes vs. no) | 2.44 | 2.13–2.79 | < 0.001 | 0.98 | 0.81–1.19 | 0.87 |
| Intubation (yes vs. no) | 2.75 | 2.41–3.14 | < 0.001 | 2.34 | 1.97–2.78 | < 0.001 |
| Renal replacement therapy (yes vs. no) | 2.05 | 1.71–2.47 | < 0.001 | 1.58 | 1.27–1.98 | 0.001 |
| Treatment withdrawal or withholding (yes vs. no) | 9.02 | 7.74–10.51 | < 0.001 | 8.99 | 7.62–10.61 | < 0.001 |
| b | ||||||
| Female patients | ||||||
| Age (per year) | 1.02 | 1.002–1.038 | 0.03 | 1.02 | 0.99–1.04 | 0.17 |
| SOFA (per point) | 1.22 | 1.19–1.14 | < 0.001 | 1.14 | 1.11–1.17 | < 0.001 |
| Frailty (per CFS point) | 1.22 | 1.17–1.27 | < 0.001 | 1.16 | 1.10–1.21 | < 0.001 |
| Vasoactive drug (yes/no) | 3.09 | 2.67–3.57 | < 0.001 | 1.27 | 1.03–1.55 | 0.02 |
| Intubation (yes/no) | 3.63 | 3.15–4.18 | < 0.001 | 2.53 | 2.08–3.07 | < 0.001 |
| Renal replacement therapy (yes/no) | 3.52 | 2.73–4.52 | < 0.001 | 3.34 | 1.74–3.15 | < 0.001 |
| Treatment withdrawal or withholding (yes/no) | 6.95 | 5.96–8.10 | < 0.001 | 8.15 | 6.83–9.72 | < 0.001 |
OR odds ratio, aOR adjusted OR, SOFA Sequential Organ Failure Assessment, CFS Clinical Frailty Scale.