Table 2.
Treatment | p-value | Adj. p.value |
---|---|---|
siRNA-comb MT2A | 5.289 × 10–7 | 9.917 × 10–7 |
siRNA1 MT2A | 5.289 × 10–7 | 9.917 × 10–7 |
siRNA2 MT1A | 5.289 × 10–7 | 9.917 × 10–7 |
siRNA2 MT2A | 5.289 × 10–7 | 9.917 × 10–7 |
siRNA3 MT2A | 5.289 × 10–7 | 9.917 × 10–7 |
siRNA4 MT1A | 1.997 × 10–7 | 9.917 × 10–7 |
siRNA4 MT1B | 5.289 × 10–7 | 9.917 × 10–7 |
siRNA4 MT2A | 5.289 × 10–7 | 9.917 × 10–7 |
siRNA2 MT1B | 1.582 × 10–5 | 2.637 × 10–5 |
siRNA1 MT1B | 1.784 × 10–5 | 2.677 × 10–5 |
siRNA1 MT1A | 2.560 × 10–5 | 3.491 × 10–5 |
siRNA-comb MT1B | 6.050 × 10–4 | 7.562 × 10–4 |
siRNA3 MT1A | 5.806 × 10–3 | 6.699 × 10–3 |
siRNA3 MT1B | 1.305 × 10–2 | 1.398 × 10–2 |
siRNA-comb MT1A | 9.857 × 10–1 | 9.857 × 10–1 |
Significant reduction of MT2A expression could be detected with a median estimate of 73% (confidence interval (95%) between 64 and 79%). P-values were FDR-adjusted.