Table 1.

Sequence and physiochemical properties of de novo designed ACPs.

Peptide	Sequencea	Sequence length	Formal chargeb	logD	Hydrophobic moment
MAD1	KRWHWWRRHWVVW-NH2	13	+ 7	− 3.41	14.828
DAP1	LWKRWVGVWRKWL-NH2	13	+ 5	− 3.23	13.879
DAP2	RWGKWFKKNSHLS-NH2	13	+ 5	− 9.37	15.250
AMP1	WKWLKKWIK-NH2	9	+ 4	− 6.46	13.449
AMP2	KRWWKWWRR-NH2	9	+ 5	− 6.90	15.084

^aAll peptides are prepared with amidated C-terminus

^bFormal charge includes N-terminal amine. Histidine considered partially protonated for purposes of formal charge calculation