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Minimum inhibitory concentration (MIC) of de novo ACPs.
| Bacteria | MIC (μM) | |||
|---|---|---|---|---|
| MAD1 | DAP1 | DAP2 | ||
| Gram Positive | B. subtilis (168) | 0.2 | < 0.6 | > 80 |
| MS S. aureus | > 80a | 7 | > 80 | |
| MR S. aureus | > 80a | 5 | > 80 | |
| Gram Negative | P. aeruginosa | 50a | 20 | > 80 |
| E. coli | 25 | 10 | > 80 | |
| Mycobacteria | M. tuberculosis | 2.5a | 20 | > 80 |
aData reported in Ref. 38
