Table 12.
Five-Year Total, Annual Average Totala, and Average Annual Age-Adjusted Incidence Ratesb with 95% Confidence Intervals for Brain and Other Central Nervous System Tumors by Major Histology Grouping, Histology, and Racec, CBTRUS Statistical Report: U.S. Cancer Statistics – U.S. Cancer Statistics - NPCR and SEER, 2013-2017
| Histology | White | Black | American Indian/Alaska Native | Asian/Pacific Islander | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5 year total | Annual average | Rate | 95% CI | 5 year total | Annual average | Rate | 95% CI | 5 year total | Annual average | Rate | 95% CI | 5 year total | Annual average | Rate | 95% CI | |
| Tumors of Neuroepithelial Tissue | 99,024 | 19,805 | 7.10 | 7.06-7.15 | 8,501 | 1,700 | 3.92 | 3.84-4.01 | 632 | 126 | 3.10 | 2.85-3.37 | 2,561 | 512 | 2.69 | 2.59-2.80 |
| Pilocytic Astrocytoma | 4,195 | 839 | 0.38 | 0.37-0.39 | 621 | 124 | 0.26 | 0.24-0.29 | 35 | 7 | 0.14 | 0.10-0.19 | 120 | 24 | 0.13 | 0.11-0.16 |
| Diffuse Astrocytoma | 6,406 | 1,281 | 0.49 | 0.48-0.50 | 592 | 118 | 0.27 | 0.25-0.29 | 59 | 12 | 0.28 | 0.21-0.36 | 191 | 38 | 0.20 | 0.17-0.23 |
| Anaplastic Astrocytoma | 6,300 | 1,260 | 0.47 | 0.45-0.48 | 466 | 93 | 0.22 | 0.20-0.24 | 38 | 8 | 0.18 | 0.12-0.25 | 189 | 38 | 0.19 | 0.16-0.22 |
| Unique Astrocytoma Variants | 896 | 179 | 0.07 | 0.07-0.08 | 142 | 28 | 0.06 | 0.05-0.07 | -- | -- | -- | -- | 47 | 9 | 0.05 | 0.04-0.07 |
| Malignant | 639 | 128 | 0.05 | 0.05-0.06 | 76 | 15 | 0.03 | 0.03-0.04 | -- | -- | -- | -- | 31 | 6 | 0.03 | 0.02-0.04 |
| Non-Malignant | 257 | 51 | 0.02 | 0.02-0.03 | 66 | 13 | 0.03 | 0.02-0.04 | -- | -- | -- | -- | 16 | 3 | 0.02 | 0.01-0.03 |
| Glioblastoma | 54,211 | 10,842 | 3.51 | 3.48-3.54 | 3,683 | 737 | 1.77 | 1.71-1.83 | 264 | 53 | 1.49 | 1.30-1.69 | 1,107 | 221 | 1.18 | 1.11-1.25 |
| Oligodendroglioma | 3,242 | 648 | 0.26 | 0.25-0.27 | 244 | 49 | 0.12 | 0.10-0.13 | 29 | 6 | 0.13 | 0.09-0.19 | 85 | 17 | 0.08 | 0.07-0.10 |
| Anaplastic Oligodendroglioma | 1,627 | 325 | 0.12 | 0.12-0.13 | 102 | 20 | 0.05 | 0.04-0.06 | -- | -- | -- | -- | 67 | 13 | 0.07 | 0.05-0.09 |
| Oligoastrocytic Tumors | 1,398 | 280 | 0.11 | 0.11-0.12 | 85 | 17 | 0.04 | 0.03-0.05 | -- | -- | -- | -- | 43 | 9 | 0.04 | 0.03-0.06 |
| Ependymal Tumors | 5,837 | 1,167 | 0.46 | 0.45-0.47 | 576 | 115 | 0.26 | 0.24-0.28 | 41 | 8 | 0.18 | 0.13-0.25 | 179 | 36 | 0.18 | 0.16-0.21 |
| Malignant | 3,316 | 663 | 0.26 | 0.25-0.27 | 381 | 76 | 0.17 | 0.15-0.19 | 18 | 4 | 0.08 | 0.05-0.12 | 129 | 26 | 0.13 | 0.11-0.16 |
| Non-Malignant | 2,521 | 504 | 0.19 | 0.19-0.20 | 195 | 39 | 0.09 | 0.08-0.10 | 23 | 5 | 0.11 | 0.07-0.16 | 50 | 10 | 0.05 | 0.04-0.07 |
| Glioma Malignant, NOS | 6,703 | 1,341 | 0.53 | 0.52-0.54 | 881 | 176 | 0.40 | 0.37-0.43 | 55 | 11 | 0.26 | 0.19-0.34 | 205 | 41 | 0.22 | 0.19-0.25 |
| Choroid Plexus Tumors | 697 | 139 | 0.06 | 0.05-0.06 | 72 | 14 | 0.03 | 0.02-0.04 | -- | -- | -- | -- | -- | -- | -- | -- |
| Malignant | 99 | 20 | 0.01 | 0.01-0.01 | 18 | 4 | 0.01 | 0.00-0.01 | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 598 | 120 | 0.05 | 0.05-0.05 | 54 | 11 | 0.02 | 0.02-0.03 | -- | -- | -- | -- | -- | -- | -- | -- |
| Other Neuroepithelial Tumors | 81 | 16 | 0.01 | 0.01-0.01 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Malignant | 48 | 10 | 0.00 | 0.00-0.01 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 33 | 7 | 0.00 | 0.00-0.00 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Neuronal and Mixed Neuronal Glial Tumors | 4,064 | 813 | 0.34 | 0.33-0.35 | 514 | 103 | 0.23 | 0.21-0.25 | 35 | 7 | 0.14 | 0.10-0.20 | 158 | 32 | 0.16 | 0.14-0.19 |
| Malignant | 806 | 161 | 0.06 | 0.06-0.06 | 70 | 14 | 0.03 | 0.03-0.04 | -- | -- | -- | -- | 36 | 7 | 0.04 | 0.03-0.05 |
| Non-Malignant | 3,258 | 652 | 0.28 | 0.27-0.29 | 444 | 89 | 0.19 | 0.17-0.21 | 28 | 6 | 0.11 | 0.07-0.16 | 122 | 24 | 0.13 | 0.10-0.15 |
| Tumors of the Pineal Region | 622 | 124 | 0.05 | 0.05-0.05 | 111 | 22 | 0.05 | 0.04-0.06 | -- | -- | -- | -- | 22 | 4 | 0.02 | 0.01-0.04 |
| Malignant | 331 | 66 | 0.03 | 0.02-0.03 | 79 | 16 | 0.03 | 0.03-0.04 | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 291 | 58 | 0.02 | 0.02-0.03 | 32 | 6 | 0.01 | 0.01-0.02 | -- | -- | -- | -- | -- | -- | -- | -- |
| Embryonal Tumors | 2,745 | 549 | 0.25 | 0.24-0.26 | 399 | 80 | 0.17 | 0.15-0.18 | 35 | 7 | 0.14 | 0.10-0.19 | 130 | 26 | 0.15 | 0.12-0.17 |
| Tumors of Cranial and Spinal Nerves | 30,265 | 6,053 | 2.13 | 2.11-2.16 | 2,241 | 448 | 1.05 | 1.01-1.10 | 227 | 45 | 1.11 | 0.97-1.27 | 1,662 | 332 | 1.66 | 1.58-1.75 |
| Nerve Sheath Tumors | 30,231 | 6,046 | 2.13 | 2.11-2.16 | 2,238 | 448 | 1.05 | 1.00-1.09 | 226 | 45 | 1.11 | 0.96-1.27 | 1,661 | 332 | 1.66 | 1.58-1.75 |
| Malignant | 171 | 34 | 0.01 | 0.01-0.01 | 27 | 5 | 0.01 | 0.01-0.02 | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 30,060 | 6,012 | 2.12 | 2.09-2.14 | 2,211 | 442 | 1.04 | 0.99-1.08 | 225 | 45 | 1.10 | 0.96-1.26 | 1,647 | 329 | 1.65 | 1.57-1.73 |
| Other Tumors of Cranial and Spinal Nerves | 34 | 7 | 0.00 | 0.00-0.00 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Tumors of Meninges | 132,895 | 26,579 | 8.90 | 8.85-8.95 | 20,560 | 4,112 | 10.44 | 10.29-10.59 | 964 | 193 | 5.70 | 5.32-6.09 | 5,871 | 1,174 | 6.49 | 6.33-6.67 |
| Meningioma | 129,114 | 25,823 | 8.61 | 8.56-8.66 | 20,081 | 4,016 | 10.22 | 10.08-10.37 | 939 | 188 | 5.59 | 5.22-5.98 | 5,709 | 1,142 | 6.33 | 6.16-6.50 |
| Malignant | 1,368 | 274 | 0.09 | 0.09-0.10 | 261 | 52 | 0.13 | 0.12-0.15 | -- | -- | -- | -- | 82 | 16 | 0.09 | 0.07-0.11 |
| Non-Malignant | 127,746 | 25,549 | 8.52 | 8.47-8.57 | 19,820 | 3,964 | 10.09 | 9.95-10.24 | -- | -- | -- | -- | 5,627 | 1,125 | 6.24 | 6.07-6.41 |
| Mesenchymal Tumors | 1,216 | 243 | 0.09 | 0.09-0.10 | 144 | 29 | 0.07 | 0.06-0.08 | -- | -- | -- | -- | 60 | 12 | 0.06 | 0.05-0.08 |
| Primary Melanocytic Lesions | 99 | 20 | 0.01 | 0.01-0.01 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Other Neoplasms Related to the Meninges | 2,466 | 493 | 0.19 | 0.18-0.19 | 330 | 66 | 0.15 | 0.13-0.17 | 19 | 4 | 0.08 | 0.05-0.13 | 100 | 20 | 0.10 | 0.08-0.12 |
| Lymphoma and Hematopoietic Neoplasms | 6,854 | 1,371 | 0.45 | 0.44-0.46 | 653 | 131 | 0.32 | 0.29-0.34 | 51 | 10 | 0.29 | 0.21-0.39 | 417 | 83 | 0.45 | 0.41-0.50 |
| Lymphoma | 6,678 | 1,336 | 0.44 | 0.43-0.45 | 619 | 124 | 0.30 | 0.28-0.33 | 48 | 10 | 0.28 | 0.20-0.37 | 405 | 81 | 0.44 | 0.39-0.48 |
| Other Hematopoietic Neoplasms | 176 | 35 | 0.01 | 0.01-0.02 | 34 | 7 | 0.02 | 0.01-0.02 | -- | -- | -- | -- | -- | -- | -- | -- |
| Germ Cell Tumors and Cysts | 1,238 | 248 | 0.11 | 0.10-0.11 | 167 | 33 | 0.07 | 0.06-0.08 | -- | -- | -- | -- | 118 | 24 | 0.13 | 0.11-0.15 |
| Germ Cell Tumors, Cysts and Heterotopias | 1,238 | 248 | 0.11 | 0.10-0.11 | 167 | 33 | 0.07 | 0.06-0.08 | -- | -- | -- | -- | 118 | 24 | 0.13 | 0.11-0.15 |
| Malignant | 840 | 168 | 0.08 | 0.07-0.08 | 113 | 23 | 0.05 | 0.04-0.06 | -- | -- | -- | -- | 100 | 20 | 0.11 | 0.09-0.13 |
| Non-Malignant | 398 | 80 | 0.03 | 0.03-0.04 | 54 | 11 | 0.02 | 0.02-0.03 | -- | -- | -- | -- | 18 | 4 | 0.02 | 0.01-0.03 |
| Tumors of Sellar Region | 52,691 | 10,538 | 3.97 | 3.93-4.00 | 14,603 | 2,921 | 7.00 | 6.88-7.11 | 629 | 126 | 3.10 | 2.85-3.36 | 2,913 | 583 | 2.96 | 2.85-3.07 |
| Tumors of the Pituitary | 50,437 | 10,087 | 3.79 | 3.76-3.83 | 13,964 | 2,793 | 6.70 | 6.59-6.82 | 603 | 121 | 2.97 | 2.73-3.23 | 2,784 | 557 | 2.82 | 2.72-2.93 |
| Malignant | 102 | 20 | 0.01 | 0.01-0.01 | 28 | 6 | 0.01 | 0.01-0.02 | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 50,335 | 10,067 | 3.78 | 3.75-3.82 | 13,936 | 2,787 | 6.69 | 6.57-6.80 | 600 | 120 | 2.96 | 2.72-3.22 | 2,781 | 556 | 2.82 | 2.71-2.93 |
| Craniopharyngioma | 2,254 | 451 | 0.18 | 0.17-0.18 | 639 | 128 | 0.29 | 0.27-0.32 | 26 | 5 | 0.12 | 0.08-0.19 | 129 | 26 | 0.14 | 0.11-0.16 |
| Unclassified Tumors | 16,694 | 3,339 | 1.17 | 1.16-1.19 | 2,151 | 430 | 1.09 | 1.04-1.14 | 158 | 32 | 0.89 | 0.75-1.05 | 576 | 115 | 0.65 | 0.60-0.71 |
| Hemangioma | 4,739 | 948 | 0.36 | 0.35-0.37 | 562 | 112 | 0.27 | 0.24-0.29 | 61 | 12 | 0.30 | 0.23-0.39 | 216 | 43 | 0.22 | 0.19-0.26 |
| Neoplasm Unspecified | 11,823 | 2,365 | 0.81 | 0.79-0.82 | 1,547 | 309 | 0.80 | 0.76-0.84 | 96 | 19 | 0.58 | 0.46-0.72 | 349 | 70 | 0.41 | 0.37-0.46 |
| Malignant | 5,697 | 1,139 | 0.37 | 0.36-0.38 | 568 | 114 | 0.31 | 0.28-0.33 | 47 | 9 | 0.29 | 0.21-0.39 | 159 | 32 | 0.20 | 0.17-0.23 |
| Non-Malignant | 6,126 | 1,225 | 0.43 | 0.42-0.45 | 979 | 196 | 0.49 | 0.46-0.53 | 49 | 10 | 0.29 | 0.21-0.39 | 190 | 38 | 0.22 | 0.19-0.25 |
| All Other | 132 | 26 | 0.01 | 0.01-0.01 | 42 | 8 | 0.02 | 0.01-0.03 | -- | -- | -- | -- | -- | -- | -- | -- |
| TOTALd | 339,661 | 67,932 | 23.83 | 23.75-23.91 | 48,876 | 9,775 | 23.88 | 23.67-24.10 | 2,670 | 534 | 14.23 | 13.67-14.82 | 14,118 | 2,824 | 15.04 | 14.78-15.29 |
| Malignant | 107,737 | 21,547 | 7.58 | 7.54-7.63 | 9,432 | 1,886 | 4.44 | 4.34-4.53 | 692 | 138 | 3.54 | 3.26-3.83 | 3,169 | 634 | 3.38 | 3.27-3.51 |
| Non-Malignant | 231,924 | 46,385 | 16.25 | 16.18-16.32 | 39,444 | 7,889 | 19.45 | 19.25-19.65 | 1,978 | 396 | 10.69 | 10.20-11.21 | 10,949 | 2,190 | 11.65 | 11.43-11.88 |
a. Annual average cases are calculated by dividing the five- year total by five.
b. Rates are per 100,000 and are age-adjusted to the 2000 US standard population.
c. Individuals with unknown race were excluded (N = 10,086).
d. Refers to all brain tumors including histologies not presented in this table.
- Counts and rates are not presented when fewer than 20 cases were reported for the specific category. The suppressed cases are included in the counts and rates for totals.
Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results Program; CI, confidence interval; NOS, not otherwise specified