Table 13.
Five-Year Total, Annual Average Totala, and Average Annual Age-Adjusted Incidence Ratesb with 95% Confidence Intervals for Brain and Other Central Nervous System Tumors by Major Histology Grouping, Histology, Hispanic Ethnicityc, and Race, CBTRUS Statistical Report: U.S. Cancer Statistics – NPCR and SEER, 2013-2017
| Histology | All Hispanic | White Hispanic | Black Hispanic | All Non-Hispanic | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5 year total | Annual average | Rate | 95% CI | 5 year total | Annual average | Rate | 95% CI | 5 year total | Annual average | Rate | 95% CI | 5 year total | Annual average | Rate | 95% CI | |
| Tumors of Neuroepithelial Tissue | 11,766 | 2,353 | 5.01 | 4.92-5.11 | 10,815 | 2,163 | 5.10 | 5.00-5.20 | 291 | 58 | 2.60 | 2.27-2.97 | 101,233 | 20,247 | 6.85 | 6.81-6.89 |
| Pilocytic Astrocytoma | 812 | 162 | 0.24 | 0.23-0.26 | 732 | 146 | 0.25 | 0.23-0.27 | 22 | 4 | 0.12 | 0.07-0.19 | 4,345 | 869 | 0.38 | 0.37-0.40 |
| Diffuse Astrocytoma | 816 | 163 | 0.33 | 0.30-0.35 | 751 | 150 | 0.33 | 0.31-0.36 | 17 | 3 | 0.12 | 0.06-0.20 | 6,606 | 1,321 | 0.48 | 0.47-0.49 |
| Anaplastic Astrocytoma | 665 | 133 | 0.28 | 0.26-0.30 | 611 | 122 | 0.28 | 0.26-0.31 | 21 | 4 | 0.17 | 0.10-0.27 | 6,447 | 1,289 | 0.45 | 0.44-0.46 |
| Unique Astrocytoma Variants | 189 | 38 | 0.07 | 0.06-0.08 | 173 | 35 | 0.07 | 0.06-0.08 | -- | -- | -- | -- | 934 | 187 | 0.07 | 0.07-0.08 |
| Malignant | 113 | 23 | 0.04 | 0.03-0.05 | 106 | 21 | 0.04 | 0.04-0.05 | -- | -- | -- | -- | 656 | 131 | 0.05 | 0.05-0.05 |
| Non-Malignant | 76 | 15 | 0.02 | 0.02-0.03 | 67 | 13 | 0.02 | 0.02-0.03 | -- | -- | -- | -- | 278 | 56 | 0.02 | 0.02-0.03 |
| Glioblastoma | 4,723 | 945 | 2.46 | 2.39-2.53 | 4,414 | 883 | 2.51 | 2.44-2.59 | 118 | 24 | 1.41 | 1.15-1.71 | 55,322 | 11,064 | 3.32 | 3.29-3.35 |
| Oligodendroglioma | 429 | 86 | 0.16 | 0.15-0.18 | 395 | 79 | 0.17 | 0.15-0.19 | -- | -- | -- | -- | 3,265 | 653 | 0.25 | 0.24-0.26 |
| Anaplastic Oligodendroglioma | 235 | 47 | 0.10 | 0.08-0.11 | 214 | 43 | 0.10 | 0.08-0.11 | -- | -- | -- | -- | 1,624 | 325 | 0.12 | 0.11-0.12 |
| Oligoastrocytic Tumors | 170 | 34 | 0.07 | 0.06-0.08 | 158 | 32 | 0.07 | 0.06-0.08 | -- | -- | -- | -- | 1,401 | 280 | 0.11 | 0.10-0.11 |
| Ependymal Tumors | 962 | 192 | 0.36 | 0.34-0.39 | 868 | 174 | 0.36 | 0.34-0.39 | 20 | 4 | 0.15 | 0.08-0.24 | 5,876 | 1,175 | 0.44 | 0.42-0.45 |
| Malignant | 624 | 125 | 0.23 | 0.21-0.25 | 570 | 114 | 0.23 | 0.21-0.25 | -- | -- | -- | -- | 3,346 | 669 | 0.25 | 0.24-0.26 |
| Non-Malignant | 338 | 68 | 0.13 | 0.12-0.15 | 298 | 60 | 0.13 | 0.12-0.15 | -- | -- | -- | -- | 2,530 | 506 | 0.18 | 0.18-0.19 |
| Glioma Malignant, NOS | 1,042 | 208 | 0.40 | 0.37-0.42 | 934 | 187 | 0.40 | 0.37-0.43 | 38 | 8 | 0.29 | 0.19-0.42 | 7,047 | 1,409 | 0.54 | 0.53-0.55 |
| Choroid Plexus Tumors | 164 | 33 | 0.05 | 0.04-0.06 | 152 | 30 | 0.05 | 0.05-0.06 | -- | -- | -- | -- | 662 | 132 | 0.05 | 0.05-0.06 |
| Malignant | 26 | 5 | 0.01 | 0.00-0.01 | 24 | 5 | 0.01 | 0.00-0.01 | -- | -- | -- | -- | 102 | 20 | 0.01 | 0.01-0.01 |
| Non-Malignant | 138 | 28 | 0.05 | 0.04-0.05 | 128 | 26 | 0.05 | 0.04-0.06 | -- | -- | -- | -- | 560 | 112 | 0.05 | 0.04-0.05 |
| Other Neuroepithelial Tumors | 21 | 4 | 0.01 | 0.00-0.01 | 17 | 3 | 0.01 | 0.00-0.01 | -- | -- | -- | -- | 86 | 17 | 0.01 | 0.01-0.01 |
| Malignant | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | 52 | 10 | 0.00 | 0.00-0.01 |
| Non-Malignant | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | 34 | 7 | 0.00 | 0.00-0.00 |
| Neuronal and Mixed Neuronal Glial Tumors | 677 | 135 | 0.23 | 0.21-0.24 | 605 | 121 | 0.23 | 0.21-0.24 | 16 | 3 | 0.08 | 0.05-0.14 | 4,250 | 850 | 0.34 | 0.33-0.35 |
| Malignant | 123 | 25 | 0.05 | 0.04-0.06 | 110 | 22 | 0.05 | 0.04-0.06 | -- | -- | -- | -- | 823 | 165 | 0.06 | 0.05-0.06 |
| Non-Malignant | 554 | 111 | 0.18 | 0.16-0.19 | 495 | 99 | 0.18 | 0.16-0.20 | -- | -- | -- | -- | 3,427 | 685 | 0.28 | 0.27-0.29 |
| Tumors of the Pineal Region | 116 | 23 | 0.04 | 0.03-0.05 | 107 | 21 | 0.04 | 0.03-0.05 | -- | -- | -- | -- | 670 | 134 | 0.05 | 0.05-0.06 |
| Malignant | 76 | 15 | 0.03 | 0.02-0.03 | 70 | 14 | 0.03 | 0.02-0.03 | -- | -- | -- | -- | 370 | 74 | 0.03 | 0.03-0.03 |
| Non-Malignant | 40 | 8 | 0.02 | 0.01-0.02 | 37 | 7 | 0.02 | 0.01-0.02 | -- | -- | -- | -- | 300 | 60 | 0.02 | 0.02-0.03 |
| Embryonal Tumors | 745 | 149 | 0.22 | 0.21-0.24 | 684 | 137 | 0.23 | 0.21-0.25 | -- | -- | -- | -- | 2,698 | 540 | 0.24 | 0.23-0.25 |
| Tumors of Cranial and Spinal Nerves | 3,193 | 639 | 1.41 | 1.36-1.46 | 2,873 | 575 | 1.40 | 1.35-1.45 | 81 | 16 | 0.72 | 0.56-0.91 | 32,378 | 6,476 | 2.14 | 2.11-2.16 |
| Nerve Sheath Tumors | 3,187 | 637 | 1.41 | 1.36-1.46 | 2,867 | 573 | 1.40 | 1.34-1.45 | 81 | 16 | 0.72 | 0.56-0.91 | 32,344 | 6,469 | 2.13 | 2.11-2.16 |
| Malignant | 43 | 9 | 0.02 | 0.01-0.03 | 37 | 7 | 0.02 | 0.01-0.03 | -- | -- | -- | -- | 180 | 36 | 0.01 | 0.01-0.01 |
| Non-Malignant | 3,144 | 629 | 1.39 | 1.34-1.44 | 2,830 | 566 | 1.38 | 1.33-1.43 | 81 | 16 | 0.72 | 0.56-0.91 | 32,164 | 6,433 | 2.12 | 2.10-2.15 |
| Other Tumors of Cranial and Spinal Nerves | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | 34 | 7 | 0.00 | 0.00-0.00 |
| Tumors of Meninges | 15,869 | 3,174 | 8.44 | 8.30-8.58 | 14,496 | 2,899 | 8.43 | 8.28-8.57 | 457 | 91 | 5.62 | 5.07-6.20 | 147,677 | 29,535 | 9.21 | 9.16-9.26 |
| Meningioma | 15,254 | 3,051 | 8.20 | 8.06-8.34 | 13,927 | 2,785 | 8.18 | 8.04-8.32 | 450 | 90 | 5.57 | 5.02-6.15 | 143,716 | 28,743 | 8.93 | 8.88-8.98 |
| Malignant | 187 | 37 | 0.09 | 0.08-0.11 | 173 | 35 | 0.10 | 0.08-0.11 | -- | -- | -- | -- | 1,563 | 313 | 0.10 | 0.09-0.10 |
| Non-Malignant | 15,067 | 3,013 | 8.10 | 7.97-8.24 | 13,754 | 2,751 | 8.08 | 7.94-8.22 | 443 | 89 | 5.48 | 4.94-6.05 | 142,153 | 28,431 | 8.83 | 8.79-8.88 |
| Mesenchymal Tumors | 211 | 42 | 0.08 | 0.07-0.10 | 198 | 40 | 0.09 | 0.08-0.10 | -- | -- | -- | -- | 1,250 | 250 | 0.09 | 0.09-0.10 |
| Primary Melanocytic Lesions | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | 98 | 20 | 0.01 | 0.01-0.01 |
| Other Neoplasms Related to the Meninges | 394 | 79 | 0.16 | 0.14-0.17 | 362 | 72 | 0.16 | 0.14-0.18 | -- | -- | -- | -- | 2,613 | 523 | 0.18 | 0.18-0.19 |
| Lymphoma and Hematopoietic Neoplasms | 956 | 191 | 0.50 | 0.47-0.53 | 896 | 179 | 0.51 | 0.48-0.55 | 18 | 4 | 0.17 | 0.09-0.27 | 7,192 | 1,438 | 0.44 | 0.43-0.45 |
| Lymphoma | 924 | 185 | 0.49 | 0.45-0.52 | 868 | 174 | 0.50 | 0.47-0.54 | 18 | 4 | 0.17 | 0.09-0.27 | 6,993 | 1,399 | 0.43 | 0.42-0.44 |
| Other Hematopoietic Neoplasms | 32 | 6 | 0.01 | 0.01-0.02 | 28 | 6 | 0.01 | 0.01-0.02 | -- | -- | -- | -- | 199 | 40 | 0.01 | 0.01-0.02 |
| Germ Cell Tumors and Cysts | 347 | 69 | 0.11 | 0.10-0.12 | 314 | 63 | 0.11 | 0.10-0.12 | -- | -- | -- | -- | 1,237 | 247 | 0.11 | 0.10-0.11 |
| Germ Cell Tumors, Cysts and Heterotopias | 347 | 69 | 0.11 | 0.10-0.12 | 314 | 63 | 0.11 | 0.10-0.12 | -- | -- | -- | -- | 1,237 | 247 | 0.11 | 0.10-0.11 |
| Malignant | 251 | 50 | 0.07 | 0.07-0.08 | 226 | 45 | 0.08 | 0.07-0.09 | -- | -- | -- | -- | 843 | 169 | 0.07 | 0.07-0.08 |
| Non-Malignant | 96 | 19 | 0.03 | 0.03-0.04 | 88 | 18 | 0.03 | 0.03-0.04 | -- | -- | -- | -- | 394 | 79 | 0.03 | 0.03-0.04 |
| Tumors of Sellar Region | 11,655 | 2,331 | 4.86 | 4.77-4.95 | 10,443 | 2,089 | 4.82 | 4.72-4.91 | 400 | 80 | 3.54 | 3.17-3.94 | 61,618 | 12,324 | 4.32 | 4.29-4.36 |
| Tumors of the Pituitary | 11,184 | 2,237 | 4.68 | 4.59-4.77 | 10,011 | 2,002 | 4.64 | 4.54-4.73 | 386 | 77 | 3.45 | 3.08-3.85 | 58,960 | 11,792 | 4.13 | 4.09-4.16 |
| Malignant | 25 | 5 | 0.01 | 0.01-0.02 | 21 | 4 | 0.01 | 0.01-0.02 | -- | -- | -- | -- | 117 | 23 | 0.01 | 0.01-0.01 |
| Non-Malignant | 11,159 | 2,232 | 4.67 | 4.58-4.76 | 9,990 | 1,998 | 4.63 | 4.53-4.72 | 386 | 77 | 3.45 | 3.08-3.85 | 58,843 | 11,769 | 4.12 | 4.08-4.15 |
| Craniopharyngioma | 471 | 94 | 0.18 | 0.16-0.19 | 432 | 86 | 0.18 | 0.16-0.20 | -- | -- | -- | -- | 2,658 | 532 | 0.20 | 0.19-0.21 |
| Unclassified Tumors | 2,394 | 479 | 1.15 | 1.10-1.20 | 2,187 | 437 | 1.16 | 1.11-1.22 | 63 | 13 | 0.65 | 0.48-0.86 | 17,658 | 3,532 | 1.16 | 1.15-1.18 |
| Hemangioma | 850 | 170 | 0.35 | 0.33-0.38 | 782 | 156 | 0.36 | 0.33-0.39 | 21 | 4 | 0.16 | 0.09-0.26 | 4,876 | 975 | 0.35 | 0.34-0.36 |
| Neoplasm Unspecified | 1,524 | 305 | 0.79 | 0.75-0.83 | 1,389 | 278 | 0.79 | 0.75-0.84 | 42 | 8 | 0.49 | 0.34-0.69 | 12,608 | 2,522 | 0.81 | 0.79-0.82 |
| Malignant | 600 | 120 | 0.35 | 0.32-0.38 | 555 | 111 | 0.35 | 0.32-0.38 | -- | -- | -- | -- | 5,987 | 1,197 | 0.36 | 0.36-0.37 |
| Non-Malignant | 924 | 185 | 0.44 | 0.41-0.47 | 834 | 167 | 0.44 | 0.41-0.47 | -- | -- | -- | -- | 6,621 | 1,324 | 0.44 | 0.43-0.45 |
| All Other | 20 | 4 | 0.01 | 0.01-0.02 | 16 | 3 | 0.01 | 0.01-0.02 | -- | -- | -- | -- | 174 | 35 | 0.01 | 0.01-0.01 |
| TOTAL d | 46,180 | 9,236 | 21.48 | 21.27-21.69 | 42,024 | 8,405 | 21.53 | 21.31-21.75 | 1,321 | 264 | 13.36 | 12.57-14.18 | 368,993 | 73,799 | 24.23 | 24.15-24.31 |
| Malignant | 12,782 | 2,556 | 5.70 | 5.60-5.81 | 11,795 | 2,359 | 5.81 | 5.70-5.93 | 308 | 62 | 2.83 | 2.48-3.21 | 110,653 | 22,131 | 7.33 | 7.29-7.37 |
| Non-Malignant | 33,398 | 6,680 | 15.78 | 15.60-15.96 | 30,229 | 6,046 | 15.72 | 15.53-15.90 | 1,013 | 203 | 10.54 | 9.83-11.28 | 258,340 | 51,668 | 16.90 | 16.84-16.97 |
a. Annual average cases are calculated by dividing the five year total by five.
b. Rates are per 100,000 and are age-adjusted to the 2000 US standard population.
c. Hispanic ethnicity is not mutually exclusive of race; Classified using the North American Association of Central Cancer Registries Hispanic Identification Algorithm, version 2 (NHIA v2).
d. Refers to all brain tumors including histologies not presented in this table.
- Counts and rates are not presented when fewer than 20 cases were reported for the specific category. The suppressed cases are included in the counts and rates for totals.
Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results Program; CI, confidence interval; NOS, not otherwise specified