Table 15.
Five-Year Total, Annual Average Totala, and Average Annual Age-Adjusted Incidence Ratesb with 95% Confidence Intervals for Children and Adolescents (Age 0-19 Years), Brain and Other Central Nervous System Tumors by Major Histology Grouping, Histology, and Racec, CBTRUS Statistical Report: U.S. Cancer Statistics – NPCR and SEER, 2013-2017
| Histology | White | Black | American Indian/Alaska Native | Asian/Pacific Islander | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5 year total | Annual average | Rate | 95% CI | 5 year total | Annual average | Rate | 95% CI | 5 year total | Annual average | Rate | 95% CI | 5 year total | Annual average | Rate | 95% CI | |
| Tumors of Neuroepithelial Tissue | 12,466 | 2,493 | 4.06 | 3.99-4.13 | 2,030 | 406 | 2.97 | 2.85-3.11 | 135 | 27 | 1.78 | 1.50-2.11 | 512 | 102 | 2.05 | 1.88-2.24 |
| Pilocytic Astrocytoma | 3,014 | 603 | 0.98 | 0.95-1.02 | 457 | 91 | 0.67 | 0.61-0.73 | 28 | 6 | 0.37 | 0.25-0.53 | 89 | 18 | 0.36 | 0.29-0.44 |
| Diffuse Astrocytoma | 754 | 151 | 0.25 | 0.23-0.26 | 113 | 23 | 0.17 | 0.14-0.20 | -- | -- | -- | -- | 33 | 7 | 0.13 | 0.09-0.19 |
| Anaplastic Astrocytoma | 311 | 62 | 0.10 | 0.09-0.11 | 50 | 10 | 0.07 | 0.05-0.10 | -- | -- | -- | -- | 19 | 4 | 0.08 | 0.05-0.12 |
| Unique Astrocytoma Variants | 373 | 75 | 0.12 | 0.11-0.13 | 73 | 15 | 0.11 | 0.08-0.14 | -- | -- | -- | -- | 17 | 3 | 0.07 | 0.04-0.11 |
| Malignant | 195 | 39 | 0.06 | 0.05-0.07 | 24 | 5 | 0.04 | 0.02-0.05 | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 178 | 36 | 0.06 | 0.05-0.07 | 49 | 10 | 0.07 | 0.05-0.10 | -- | -- | -- | -- | -- | -- | -- | -- |
| Glioblastoma | 550 | 110 | 0.18 | 0.16-0.19 | 94 | 19 | 0.14 | 0.11-0.17 | -- | -- | -- | -- | 35 | 7 | 0.14 | 0.10-0.20 |
| Oligodendroglioma | 137 | 27 | 0.04 | 0.04-0.05 | 23 | 5 | 0.03 | 0.02-0.05 | -- | -- | -- | -- | -- | -- | -- | -- |
| Anaplastic Oligodendroglioma | 18 | 4 | 0.01 | 0.00-0.01 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Oligoastrocytic Tumors | 54 | 11 | 0.02 | 0.01-0.02 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Ependymal Tumors | 960 | 192 | 0.31 | 0.29-0.33 | 144 | 29 | 0.21 | 0.18-0.25 | -- | -- | -- | -- | 43 | 9 | 0.17 | 0.12-0.23 |
| Malignant | 791 | 158 | 0.26 | 0.24-0.28 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 169 | 34 | 0.05 | 0.05-0.06 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Glioma Malignant, NOS | 2,331 | 466 | 0.76 | 0.73-0.79 | 417 | 83 | 0.61 | 0.55-0.67 | 24 | 5 | 0.31 | 0.20-0.47 | 82 | 16 | 0.33 | 0.26-0.41 |
| Choroid Plexus Tumors | 327 | 65 | 0.11 | 0.10-0.12 | 50 | 10 | 0.07 | 0.05-0.10 | -- | -- | -- | -- | -- | -- | -- | -- |
| Malignant | 78 | 16 | 0.03 | 0.02-0.03 | 16 | 3 | 0.02 | 0.01-0.04 | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 249 | 50 | 0.08 | 0.07-0.09 | 34 | 7 | 0.05 | 0.03-0.07 | -- | -- | -- | -- | -- | -- | -- | -- |
| Other Neuroepithelial Tumors | 24 | 5 | 0.01 | 0.01-0.01 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Malignant | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Neuronal and Mixed Neuronal Glial Tumors | 1,537 | 307 | 0.50 | 0.47-0.52 | 247 | 49 | 0.36 | 0.32-0.41 | 16 | 3 | 0.21 | 0.12-0.35 | 59 | 12 | 0.24 | 0.18-0.31 |
| Malignant | 86 | 17 | 0.03 | 0.02-0.03 | 18 | 4 | 0.03 | 0.02-0.04 | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 1,451 | 290 | 0.47 | 0.45-0.50 | 229 | 46 | 0.34 | 0.29-0.38 | -- | -- | -- | -- | -- | -- | -- | -- |
| Tumors of the Pineal Region | 140 | 28 | 0.05 | 0.04-0.05 | 49 | 10 | 0.07 | 0.05-0.10 | -- | -- | -- | -- | -- | -- | -- | -- |
| Malignant | 109 | 22 | 0.04 | 0.03-0.04 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 31 | 6 | 0.01 | 0.01-0.01 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Embryonal Tumors | 1,936 | 387 | 0.63 | 0.61-0.66 | 298 | 60 | 0.43 | 0.39-0.49 | 26 | 5 | 0.34 | 0.22-0.49 | 111 | 22 | 0.44 | 0.36-0.53 |
| Medulloblastoma | 1,300 | 260 | 0.43 | 0.40-0.45 | 173 | 35 | 0.25 | 0.22-0.29 | 18 | 4 | 0.24 | 0.14-0.37 | 77 | 15 | 0.31 | 0.24-0.38 |
| Primitive neuroectodermal tumors | 183 | 37 | 0.06 | 0.05-0.07 | 39 | 8 | 0.06 | 0.04-0.08 | -- | -- | -- | -- | -- | -- | -- | -- |
| Atypical teratoid rhabdoid tumor | 280 | 56 | 0.09 | 0.08-0.10 | 59 | 12 | 0.08 | 0.06-0.11 | -- | -- | -- | -- | 19 | 4 | 0.08 | 0.05-0.12 |
| Other embryonal histologies | 173 | 35 | 0.06 | 0.05-0.07 | 27 | 5 | 0.04 | 0.03-0.06 | -- | -- | -- | -- | -- | -- | -- | -- |
| Tumors of Cranial and Spinal Nerves | 1,002 | 200 | 0.32 | 0.30-0.35 | 162 | 32 | 0.24 | 0.20-0.28 | -- | -- | -- | -- | 44 | 9 | 0.18 | 0.13-0.24 |
| Nerve Sheath Tumors | 999 | 200 | 0.32 | 0.30-0.34 | 162 | 32 | 0.24 | 0.20-0.28 | -- | -- | -- | -- | 44 | 9 | 0.18 | 0.13-0.24 |
| Malignant | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | 44 | 9 | 0.18 | 0.13-0.24 |
| Other Tumors of Cranial and Spinal Nerves | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Tumors of Meninges | 894 | 179 | 0.29 | 0.27-0.31 | 150 | 30 | 0.22 | 0.19-0.26 | -- | -- | -- | -- | 33 | 7 | 0.13 | 0.09-0.19 |
| Meningioma | 506 | 101 | 0.16 | 0.15-0.18 | 94 | 19 | 0.14 | 0.11-0.17 | -- | -- | -- | -- | 19 | 4 | 0.08 | 0.05-0.12 |
| Malignant | 28 | 6 | 0.01 | 0.01-0.01 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 478 | 96 | 0.15 | 0.14-0.17 | -- | -- | -- | -- | -- | -- | -- | -- | 19 | 4 | 0.08 | 0.05-0.12 |
| Mesenchymal Tumors | 209 | 42 | 0.07 | 0.06-0.08 | 32 | 6 | 0.05 | 0.03-0.07 | -- | -- | -- | -- | -- | -- | -- | -- |
| Primary Melanocytic Lesions | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Other Neoplasms Related to the Meninges | 168 | 34 | 0.05 | 0.05-0.06 | 24 | 5 | 0.04 | 0.02-0.05 | -- | -- | -- | -- | -- | -- | -- | -- |
| Lymphoma and Hematopoietic Neoplasms | 89 | 18 | 0.03 | 0.02-0.04 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Lymphoma | 42 | 8 | 0.01 | 0.01-0.02 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Other Hematopoietic Neoplasms | 47 | 9 | 0.02 | 0.01-0.02 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Germ Cell Tumors and Cysts | 756 | 151 | 0.25 | 0.23-0.26 | 106 | 21 | 0.16 | 0.13-0.19 | -- | -- | -- | -- | 87 | 17 | 0.35 | 0.28-0.43 |
| Germ Cell Tumors, Cysts and Heterotopias | 756 | 151 | 0.25 | 0.23-0.26 | 106 | 21 | 0.16 | 0.13-0.19 | -- | -- | -- | -- | 87 | 17 | 0.35 | 0.28-0.43 |
| Malignant | 588 | 118 | 0.19 | 0.18-0.21 | 79 | 16 | 0.12 | 0.09-0.15 | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 168 | 34 | 0.05 | 0.05-0.06 | 27 | 5 | 0.04 | 0.03-0.06 | -- | -- | -- | -- | -- | -- | -- | -- |
| Tumors of Sellar Region | 3,170 | 634 | 1.02 | 0.98-1.05 | 657 | 131 | 0.96 | 0.89-1.04 | 59 | 12 | 0.80 | 0.61-1.03 | 145 | 29 | 0.59 | 0.49-0.69 |
| Tumors of the Pituitary | 2,536 | 507 | 0.81 | 0.78-0.84 | 500 | 100 | 0.73 | 0.67-0.80 | 53 | 11 | 0.72 | 0.54-0.94 | 106 | 21 | 0.43 | 0.35-0.52 |
| Malignant | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | -- | -- | -- | -- | 500 | 100 | 0.73 | 0.67-0.80 | -- | -- | -- | -- | 106 | 21 | 0.43 | 0.35-0.52 |
| Craniopharyngioma | 634 | 127 | 0.21 | 0.19-0.22 | 157 | 31 | 0.23 | 0.20-0.27 | -- | -- | -- | -- | 39 | 8 | 0.16 | 0.11-0.21 |
| Unclassified Tumors | 1,193 | 239 | 0.39 | 0.37-0.41 | 178 | 36 | 0.26 | 0.22-0.30 | 17 | 3 | 0.23 | 0.13-0.36 | 34 | 7 | 0.14 | 0.09-0.19 |
| Hemangioma | 496 | 99 | 0.16 | 0.15-0.18 | 51 | 10 | 0.07 | 0.06-0.10 | -- | -- | -- | -- | 18 | 4 | 0.07 | 0.04-0.11 |
| Neoplasm Unspecified | 671 | 134 | 0.22 | 0.20-0.24 | 115 | 23 | 0.17 | 0.14-0.20 | -- | -- | -- | -- | 16 | 3 | 0.06 | 0.04-0.10 |
| Malignant | 159 | 32 | 0.05 | 0.04-0.06 | 37 | 7 | 0.05 | 0.04-0.07 | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 512 | 102 | 0.17 | 0.15-0.18 | 78 | 16 | 0.11 | 0.09-0.14 | -- | -- | -- | -- | -- | -- | -- | -- |
| All Other | 26 | 5 | 0.01 | 0.01-0.01 | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| TOTAL d | 19,570 | 3,914 | 6.36 | 6.27-6.45 | 3,294 | 659 | 4.83 | 4.66-4.99 | 242 | 48 | 3.22 | 2.83-3.65 | 868 | 174 | 3.48 | 3.26-3.72 |
| Malignant | 11,343 | 2,269 | 3.70 | 3.63-3.77 | 1,857 | 371 | 2.72 | 2.60-2.85 | 131 | 26 | 1.73 | 1.45-2.05 | 529 | 106 | 2.12 | 1.94-2.31 |
| Non-Malignant | 8,227 | 1,645 | 2.66 | 2.60-2.72 | 1,437 | 287 | 2.11 | 2.00-2.22 | 111 | 22 | 1.49 | 1.23-1.80 | 339 | 68 | 1.36 | 1.22-1.52 |
a. Annual average cases are calculated by dividing the five year total by five.
b. Rates are per 100,000 and are age-adjusted to the 2000 US standard population.
c. Individuals with unknown race were excluded (N = 630).
d. Refers to all brain tumors including histologies not presented in this table.
- Counts and rates are not presented when fewer than 20 cases were reported for the specific category. The suppressed cases are included in the counts and rates for totals.
Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results Program; CI, confidence interval; NOS, not otherwise specified