Table 8.

Five-Year Total, Annual Average Total^a, and Average Annual Age-Adjusted Incidence Rates^b with 95% Confidence Intervals of Brain and Other Central Nervous System Tumors by Site^c and Sex, CBTRUS Statistical Report: U.S. Cancer Statistics – NPCR and SEER, 2013-2017

Site (ICD-O-3 Code)	Total					Male						Female
	5-Year total	Annual Average	% of All Tumors	Rate	95% CI	5-Year total	Annual Average	% Malignant	% Non-Malignant	Rate	95% CI	5-Year total	Annual Average	% Malignant	% Non-Malignant	Rate	95% CI
Frontal, temporal, parietal, and occipital lobes of the brain (C71.1-C71.4)	74,890	14,978	15.3%	4.23	4.20-4.26	41,746	8,349	91.7%	8.3%	4.99	4.94-5.04	33,144	6,629	88.5%	11.5%	3.57	3.53-3.61
Frontal lobe (C71.1)	32,856	6,571	7.9%	1.88	1.86-1.90	17,467	3,493	92.3%	7.7%	2.11	2.07-2.14	15,389	3,078	89.9%	10.1%	1.68	1.65-1.71
Temporal lobe (C71.2)	24,233	4,847	5.8%	1.36	1.34-1.38	14,447	2,889	90.8%	9.2%	1.72	1.69-1.74	9,786	1,957	86.8%	13.2%	1.05	1.03-1.07
Parietal lobe (C71.3)	13,987	2,797	3.4%	0.78	0.76-0.79	7,706	1,541	93.4%	6.6%	0.91	0.89-0.93	6,281	1,256	89.1%	10.9%	0.66	0.64-0.68
Occipital lobe (C71.4)	3,814	763	0.9%	0.21	0.21-0.22	2,126	425	86.4%	13.6%	0.26	0.24-0.27	1,688	338	83.8%	16.2%	0.18	0.17-0.19
Cerebrum (C71.0)	7,213	1,443	1.7%	0.42	0.41-0.43	3,872	774	83.2%	16.8%	0.47	0.46-0.49	3,341	668	79.5%	20.5%	0.38	0.37-0.39
Ventricle (C71.5)	4,097	819	1.0%	0.26	0.25-0.26	2,218	444	42.1%	57.9%	0.28	0.27-0.29	1,879	376	40.1%	59.9%	0.23	0.22-0.24
Cerebellum (C71.6)	8,892	1,778	2.1%	0.56	0.55-0.57	4,737	947	63.9%	36.1%	0.61	0.59-0.63	4,155	831	55.6%	44.4%	0.52	0.50-0.53
Brain stem (C71.7)	6,174	1,235	1.5%	0.40	0.39-0.41	3,346	669	76.1%	23.9%	0.43	0.42-0.45	2,828	566	77.4%	22.6%	0.37	0.35-0.38
Other brain (C71.8-C71.9)	33,498	6,700	8.1%	1.90	1.88-1.92	17,687	3,537	83.8%	16.2%	2.16	2.12-2.19	15,811	3,162	78.9%	21.1%	1.68	1.65-1.70
Spinal cord and cauda equina (C72.0-C72.1)	12,905	2,581	3.1%	0.77	0.76-0.79	6,782	1,356	27.6%	72.4%	0.84	0.82-0.86	6,123	1,225	26.4%	73.6%	0.71	0.70-0.73
Cranial nerves (C72.2-C72.5)	28,850	5,770	6.9%	1.65	1.63-1.67	13,501	2,700	5.7%	94.3%	1.60	1.57-1.63	15,349	3,070	5.5%	94.5%	1.70	1.67-1.72
Other nervous system (C72.8-C72.9)	2,548	510	0.6%	0.15	0.14-0.15	1,295	259	56.8%	43.2%	0.16	0.15-0.17	1,253	251	55.8%	44.2%	0.14	0.13-0.15
Meninges (cerebral and spinal) (C70.0-C70.9)	159,403	31,881	38.4%	8.84	8.79-8.88	43,365	8,673	2.2%	97.8%	5.30	5.25-5.35	116,038	23,208	1%	99%	11.97	11.90-12.04
Pituitary (C75.1-C75.2)	74,426	14,885	17.9%	4.46	4.42-4.49	33,614	6,723	0.7%	99.3%	4.07	4.03-4.12	40,812	8,162	0.5%	99.5%	4.93	4.88-4.98
Pineal (C75.3)	1,775	355	0.4%	0.11	0.11-0.12	1,040	208	75%	25%	0.13	0.13-0.14	735	147	44.8%	55.2%	0.09	0.09-0.10
Olfactory tumors of the nasal cavity (C30.0 d)	740	148	0.2%	0.04	0.04-0.05	438	88	100%	0%	0.05	0.05-0.06	302	60	100%	0%	0.03	0.03-0.04
TOTAL	415,411	83,082	100.0%	23.79	23.71-23.86	173,641	34,728	39.5%	60.5%	21.09	20.99-21.20	241,770	48,354	22.7%	77.3%	26.31	26.21-26.42

a. Annual average cases are calculated by dividing the five-year total by five.

b. Rates are per 100,000 and are age-adjusted to the 2000 US standard population.

c. The sites referred to in this table are loosely based on the categories and site codes defined in the SEER site/histology validation list.

d. ICD-O-3 histology codes 9522-9523 only.

- Counts and rates are not presented when fewer than 20 cases were reported for the specific category. The suppressed cases are included in the counts and rates for totals.

CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results Program; CI, confidence interval