Table 1.
The FFL motifs identified in nSARS-CoV-2 responsive miRNA:TF: gene coregulatory network having its target genes or TFs in the enriched pathways
| FFL | miRNA | TF | Gene | Pathways |
|---|---|---|---|---|
| A | hsa-mir-9-5p | EP300 | PLCB4 | Endosomal/Vacuolar pathway (R-HSA-1236977), Antigen Presentation: Folding, assembly, and peptide loading for MHC class 1 (R-HSA-983170) |
| B | hsa-mir-324-3p | MYC | HLA-F | Endosomal/Vacuolar pathway (R-HSA-1236977), Antigen Presentation: Folding, assembly, and peptide loading for MHC class 1 (R-HSA-983170) |
| C | hsa-mir-1827 | E2F1 | CTSV | Endosomal/Vacuolar pathway (R-HSA-1236977) |
| D | hsa-mir-1277-5p | SP1 | CANX | Antigen Presentation: Folding, assembly, and peptide loading for MHC class 1 (R-HSA-983170) |